Results 81 to 90 of about 7,361,427 (296)
The demand for higher education in the Netherlands 1950-'99 [PDF]
This paper investigates the role of economic factors in the university enrollment decision for the post-war period in the Netherlands. We include those factors standing at the heart of the idea that education is an investment.
Erik Canton, Frank de Jong
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Clinical Evaluation of Kinesio Taping Outcomes in Stage II Cellulite: A Pilot Study
Reabilitacijos Mokslai: Slauga, Kineziterapija, ErgoterapijaBackground. Cellulite is a common aesthetic condition linked to alterations in subcutaneous fat and dermal connective tissue, with possible impairment of microcirculation and lymphatic drainage. Kinesio taping (KT) is used in physiotherapy, but evidence
Laura Žalienė +7 more
doaj +1 more source
Explaining Demand for Higher Education [PDF]
, 2012 Recognizing the crucial role of higher education for the development of nations and individuals, many countries have recently established ambitious targets for the percentage of graduates in their population by 2020.
Oliveira, Manuela +2 more
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Gamificacion in education and active methodologies at Higher education [PDF]
, 2019 In recent years, there has been an increasing interest in applying Gamification in Education, which can be defined as the application of game design elements to learning activities.
Bentabol-Manzanares, Maria Amparo +8 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Higher education: Distance education and mercantilization of higher education
, 2019 Este artigo objetiva comparar, no nível do ensino superior, a educação a distância ministrada pelos conglomerados educacionais com a EaD veiculada, sobretudo, pelas universidades públicas, PUCs, e instituições ligadas à Rede Federal de Educação Profissional Científica e Tecnológica (RFEPCT).
Oliveira, Maria Auxiliadora Monteiro +1 more
openaire +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source