Results 101 to 110 of about 4,635,780 (309)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Prerequisite for Enhancing Student Learning Outcomes in Medical Education
Sultan Qaboos University Medical Journal, 2009 Anyone achieving a grade of “A” has performed at a very good level. The label, “triple A”, is sometimes used to distinguish those who are particularly outstanding.
C B Hazlett
doaj
Useless Med School Notes; Medical Education Through Mnemonics [PDF]
, 2019 BACKGROUND: The volume of content required for synthesis by medical students is immense and continues to grow as more insight and information is added to the existing compendium of medical knowledge.
Miller, Aaron B.
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Sultan Qaboos University Medical Journal, 2012 Historically, health professionals have been educated in profession-specific institutions which provide limited opportunities for learning interprofessional (IP) skills.
Ibrahim M. Inuwa
doaj
Transgender Healthcare Teaching in the Undergraduate Medical School Curriculum [PDF]
, 2018 With increasing recognition of the diverse and specific needs of transgender individuals in a health care setting, lack of knowledge, poor attitudes and prejudice towards transgender patients can result in this population being afraid to access medical ...
Donaldson, A. +3 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Question of Competence: Reconsidering Medical Education in the Twenty-First Century [PDF]
, 2013 [Excerpt] The real challenge for those involved in designing competency-based educational programs is to recognize the complexity of competence as a concept. Only then can they effectively delineate the knowledge, skills, and attitudes that learners must
Hodges, Brian D, Lingard, Lorelei
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
, 2017 Pipeline programs are designed to prepare and inspire students to pursue careers in medicine and medical research. SKMC is committed to providing experiences and education to middle school, high school, college, and graduate students from groups ...
core +1 more source