Results 121 to 130 of about 4,570,005 (290)

Assessing Digital Competence Among Health Science Undergraduates: a Critical Analysis

Revista de Investigación e Innovación en Ciencias de la Salud
Introduction. Strategic management between the educational realm and technology is possible as long as teachers and students have adequate and timely development of digital competencies. Although current generations are receptive to technology, academic
Antonieta Herrera-Lillo, Gabriela Urrejola-Contreras   +1 more
doaj   +1 more source

The Bologna Process and the reform of medical education [PDF]

, 2009
In 1988, the Magna Charta Universitatum was signed at a meeting of European University rectors on the occasion of the 900th Anniversary of the University of Bologna to mark their commitment to harmonising the European Higher Education sector ...
Vassallo, Josanne
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Understanding the consequence of COVID-19 on undergraduate medical education: Medical students' perspective. [PDF]

Ann Med Surg (Lond), 2020
Sani I, Hamza Y, Chedid Y, Amalendran J, Hamza N.   +4 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The training of the medical students of Guantánamo for the radiological diagnosis of respiratory diseases

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Background: the graduation of a competent general practitioner is a social requirement. Among his competences the physician must know how to make the radiology diagnosis of respiratory diseases.Objective: to devise a system of activities to foster the ...
Reinaldo Elias-Sierra, Karla Sucet Elias-Armas   +1 more
doaj  

Experts' consensus over key components of online learning environments in medical education: a modified e-Delphi study

Khyber Medical University Journal
Objective: To achieve expert consensus on the essential components for effective online learning environments in medical education using a modified e-Delphi approach.
Noor-i-Kiran Naeem, Siti Nurma Hanim Hadie, Irwan Mahazir Ismail, Zil-e-Fatima Naeem, Ahmad Hassan Khan, Muhamad Saiful Bahri Yusoff   +5 more
doaj   +1 more source

Impact of the COVID-19 pandemic on medical education: Medical students' knowledge, attitudes, and practices regarding electronic learning. [PDF]

PLoS One, 2020
Alsoufi A, Alsuyihili A, Msherghi A, Elhadi A, Atiyah H, Ashini A, Ashwieb A, Ghula M, Ben Hasan H, Abudabuos S, Alameen H, Abokhdhir T, Anaiba M, Nagib T, Shuwayyah A, Benothman R, Arrefae G, Alkhwayildi A, Alhadi A, Zaid A, Elhadi M.   +20 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source