Results 121 to 130 of about 1,726,771 (283)

Analysis of the Institutional Free Market in Accredited Medical Physics Graduate Programs [PDF]

open access: yesarXiv
Medical Physics education is delivered through accredited programs with admissions and funding for students determined by individual institutions providing the educational experiences. Public data from accredited graduate programs, along with funding data, were used to analyze institutional trends in this educational market.
arxiv  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Experts' consensus over key components of online learning environments in medical education: a modified e-Delphi study

open access: yesKhyber Medical University Journal
Objective: To achieve expert consensus on the essential components for effective online learning environments in medical education using a modified e-Delphi approach.
Noor-i-Kiran Naeem   +5 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

The training of the medical students of Guantánamo for the radiological diagnosis of respiratory diseases

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Background: the graduation of a competent general practitioner is a social requirement. Among his competences the physician must know how to make the radiology diagnosis of respiratory diseases.Objective: to devise a system of activities to foster the ...
Reinaldo Elias-Sierra   +1 more
doaj  

Promoting AI Competencies for Medical Students: A Scoping Review on Frameworks, Programs, and Tools [PDF]

open access: yesarXiv
As more clinical workflows continue to be augmented by artificial intelligence (AI), AI literacy among physicians will become a critical requirement for ensuring safe and ethical AI-enabled patient care. Despite the evolving importance of AI in healthcare, the extent to which it has been adopted into traditional and often-overloaded medical curricula ...
arxiv  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Educational actions to deal with student diversity in Dentistry in the context of COVID-19

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: proposing tasks and educational actions to deal with student diversity can contribute to the reorganization and the quality of the teaching-learning process in the major of dentistry, given the challenge that COVID-19 represents.Objective: to
Taimí Santos-Velázquez   +1 more
doaj  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

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