Results 211 to 220 of about 420,233 (306)

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su, Lei Chen, Seema Betigeri, Nancy Dreyer, Helga Gardarsdottir, Rachele Hendricks‐Sturrup, Mehmet Burcu   +6 more
wiley   +1 more source

Evaluation of psychological resilience and psychosocial care competencies of oncology nurses: a cross-sectional study. [PDF]

BMC Nurs
Özcan G, Özkaraman A, Özgenel F.
europepmc   +1 more source

Combined Biologics and Exclusive Enteral Nutrition Promote Early Transmural Healing and Improve Long‐Term Outcomes in Crohn's Disease: A Multicenter Retrospective Study

Clinical Pharmacology &Therapeutics, EarlyView.
Study design and flow chart. From October 2016 to 2024, we searched the Crohn’s disease (CD) patient databases of three IBD centers in Hubei Province and identified 598 CD patients. Among them, 179 were in clinical remission and 38 had mild disease and were therefore excluded based on the study criteria.
Haixia Ren, Jing An, Wei Chen, Jiao Li, Xing Li, Anning Yin, Jing Wang, Wei Wang, Jingyun Cheng, Jian Kang, Yaqing Xu, Yueyue Lu, Juan Su, Qian Zhou, Huipeng Wan, Zimeng Zhang, Ping An   +16 more
wiley   +1 more source

Resilience in nursing: a comparative analysis of hospital and primary healthcare settings. [PDF]

BMC Nurs
Duhaileb MAMA, Shdaifat EA, Shaikh AA, Majed MA, Mansour SA, Malallah FA, Khalaf MA, Matter SA.   +7 more
europepmc   +1 more source

The Feasibility and Quality of the European Prescribing Exam: An International Multicenter Pilot Study Among 3109 Medical Students From 16 Medical Schools

Clinical Pharmacology &Therapeutics, EarlyView.
The WHO Global Patient Safety Challenge “Medication Without Harm” emphasizes the need to improve doctors' prescribing competence. Junior doctors are particularly at risk of prescribing errors due to inadequate training. To address this, the European Prescribing Exam was developed to standardize and improve clinical pharmacology and therapeutics (CPT ...
Erik M. Donker, Joost D. Piët, David J. Brinkman, Milan C. Richir, Paraskevi Papaioannidou, Robert Likic, Emilio J. Sanz, Thierry Christiaens, João N. Costa, Fabrizio De Ponti, Ylva Böttiger, Cornelis Kramers, Michiel A. van Agtmael, Jelle Tichelaar, on behalf of the Erasmus+ consortium EuroPE+ and the EACPT Education Working Group, Emilio Sanz, Carla Sans, Ellen van Leeuwen, Haithem Chtioui, Joao Costa, Jitka Rychlickova, Lorena Dima, Romaldas Maciulaitis, Marc Labriffe, Bogdan Tamba, Michiel van Agtmael, Erik Donker   +26 more
wiley   +1 more source

The Supply of Investigational Medicinal Product and Management of Study Materials for Decentralized Participants—Insights from the Trials@Home RADIAL Proof‐of‐Concept Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Decentralized clinical trials (DCTs), which move trial activities to participants' homes or direct surroundings, offer potential advantages over conventional site‐based trials through reduced participant burden and improved accessibility. The direct‐to‐participant (DtP) delivery of investigational medicinal products (IMPs) and other study materials and
Megan Heath, Amos J. de Jong, Shaun Magorrian‐Spence, Chao Jin, Danny R. van Weelij, Lucas Pagnier, Yvonne van Rijswick, Volker Haufe, Bart Lagerwaard, Mira G. P. Zuidgeest, on behalf of the Trials@Home consortium   +10 more
wiley   +1 more source

Investigating the relationship between complementary and alternative therapy attitudes and pain management self-efficacy in surgical nurses: a cross-sectional study. [PDF]

BMC Nurs
Işık SA, Kaynarca S.
europepmc   +1 more source

Selecting and Preparing Clinical Sites for the Successful Conduct of Decentralized Clinical Trial Activities–Findings From the Trials@Home RADIAL Proof‐of‐Concept Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Decentralized clinical trials (DCTs) offer opportunities to improve trial accessibility, participant convenience, and efficiency, yet may pose significant operational challenges for clinical trial sites. This paper presents the operational insights gained from selecting, training, and supporting clinical sites within the RADIAL proof‐of‐concept trial ...
Katarzyna Lipinska, Danny van Weelij, Bart Lagerwaard, Linda Rutgrink, Eduard Vardianu, Petra Naster, Lina Pérez‐Breva, Paul Bodfish, Megan Heath, Yvonne van Rijswick, Diederick E. Grobbee, Mira G.P. Zuidgeest, on behalf of the Trials@Home consortium   +12 more
wiley   +1 more source

Construction of a practice model of evidence-based health service development for public health nursing in Japan: a Delphi survey. [PDF]

BMC Nurs
Okamoto R, Izumi H, Hirano M, Iwamoto S, Koide K.   +4 more
europepmc   +1 more source

Regulatory Interactions and Learnings—RADIAL the Trials@Home Proof‐of‐Concept Trial on Decentralization

Clinical Pharmacology &Therapeutics, EarlyView.
This paper is part of a series of six publications presenting lessons learned during the setup, regulatory submission, and conduct of the proof‐of‐concept Trials@Home RADIAL trial. The three‐arm RADIAL trial, comprising fully decentralized, hybrid, and conventional arms, is the first clinical study to evaluate the feasibility and acceptability of ...
Helga Gardarsdottir, Hamidou Traore, Kate Huntley, Dinesh Mistry, Amos J. de Jong, Agnes Legathe, Tim de Smedt, Scott Askin, Megan Heath, Solange Corriol‐Rohou, Bart Lagerwaard, Mira G.P. Zuidgeest, on behalf of the IMI Trials@Home Consortium   +12 more
wiley   +1 more source