Results 121 to 130 of about 3,837,676 (312)

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

open access: yesAdvanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman   +3 more
wiley   +1 more source

Combined oral contraceptives with estetrol: Reduced risk of thrombosis and other benefits. A review

open access: yesГинекология
Demographic trends indicate a decrease in the number of children per woman, a change in reproductive patterns and a late age of motherhood. These factors increase the importance of effective contraception.
N. M. Podzolkova   +3 more
doaj   +1 more source

Will scholars trump teachers in New Zealand teacher education? [PDF]

open access: yes, 2005
The Performance-Based Research Fund (PBRF) assessment process in 2003 highlighted the research imperative for academic staff in New Zealand teacher education.
Alcorn, Noeline
core   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

open access: yesAdvanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt   +14 more
wiley   +1 more source

Students’ views on HE learning environments for professional teacher education [PDF]

open access: yes
There is a national debate about the connection between the physical environment and learning (McGregor, 2004) and the importance of designing the physical space to enhance the quality of learning (DfES, 2004, 2006, 2007; JISC, 2006; SMG 2006).
Shelton Mayes, Ann, Stoncel, Diane
core  

Experiences from the academic training. Study about the identity of the novice teacher, second part. [PDF]

open access: yes, 2015
We present some progresses of the current research project we are developing called "The professional identity of teacher studies”. It aims to analyse the training received by students in the faculties of education in the Autonomous Community of ...
Cortés González, Pablo   +2 more
core  

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

open access: yesAdvanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng   +10 more
wiley   +1 more source

Redesigning Instruction for Inter-Professional Education [PDF]

open access: yes, 2016
Purpose: A pilot project created a curriculum model infusing Interprofessional Education (IPE) in Mercy College’s School of Health and Natural Sciences (SHNS), allowing students and faculty to integrate IPE within programmatic courses.
Hyland, PT, PhD, Nannette   +2 more
core   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

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