Results 51 to 60 of about 11,102,286 (369)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

The bumpy road to change: a retrospective qualitative study on formerly detained adolescents’ trajectories towards better lives

Child and Adolescent Psychiatry and Mental Health, 2019
Background Currently, the risk-oriented focus in forensic youth care is increasingly complemented by a growing interest in strengths-based approaches.
Nele Van Hecke, Wouter Vanderplasschen, Lore Van Damme, Stijn Vandevelde   +3 more
doaj   +1 more source

On the necessary co-existence of special and inclusive education

International Journal of Inclusive Education, 2019
While many distinctions between ‘special’ and ‘inclusive’ education have been made and continue to be forcefully debated, the two concepts remain strongly evident in policy and practice in many countries.
L. Florian
semanticscholar   +1 more source

Special Education in China: How Culture Affects Special Education [PDF]

, 2019
Undergraduate Theoretical ...
Hosek, Melissa
core   +1 more source

Teaching Students with Special Needs in School-Based, Agricultural Education: A Historical Inquiry

, 2020
The purpose of this historical study was to investigate the inclusion of students with special needs in school-based, agricultural education as reported by The Agricultural Education Magazine and the Journal of Agricultural Education over a time period ...
Edwards, M. Craig, Teixeira, Kathryn L
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Storytelling Method using Finger Pool to Improve the Expressive Language Ability of Moderately Independent Students Class II SDN Raharja Tanjungsari

Journal of Education for Sustainability and Diversity, 2023
The purpose of this research is to improve the expressive language skills of mentally retarded students in class II SLB Raharja Mandiri using the storytelling method through finger puppet media. This study uses the Mix Methods Research method, which is a
Mochamad Farhan, Endang Rochyadi, Iding Tarsidi, Ranti Novianti   +3 more
doaj   +1 more source

(Special) Education is Political; (Special) Education is Social Justice

Journal of Critical Thought and Praxis, 2020
Though treated as neutral and apolitical by schools, teachers, scholars, and administrators, special education is fraught with inequality and loaded language, and can function to segregate and disempower students. The debate over who is worthy of education–and what kind of education–is intimately tied to conceptions of dis/ability.
Lilly B. Padía, Rachel Elizabeth Traxler   +1 more
openaire   +3 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Vulnerability to bullying in children with a history of specific speech and language difficulties [PDF]

, 2008
This is an electronic version of an article published in Lindsay, Geoff and Dockrell, Julie and Mackie, Clare (2008) Vulnerability to bullying in children with a history of specific speech and language difficulties.
Ahmad Y., Arora C.M.J., Bishop D.V.M., Brinton B., Clare Mackie, Craig W.M., Dunn L.M., Elliott C.D., Fujiki M., Geoff Lindsay, Harter S., Julie E. Dockrell, Leonard L.B., Martlew M., Neale M., Olweus D., O’Moore A.M., Plante E., Redmond S., Renfrew K., Seals D., Semel E., Smith P.   +22 more
core   +2 more sources