Results 81 to 90 of about 8,102,852 (300)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Specialusis Ugdymas, 2017 Learning software for children with intellectual disabilities is particularly important because some of the solutions are highly practical, allowing for easy presentation of different types of incentives and goals, often with higher quality than other ...
Efstratios Pantelis, Nikolay Tsankov
doaj +1 more source
Augmented reality in special education: a meta-analysis of single-subject design studies
European Journal of Special Needs Education, 2019 There is a growing interest in using augmented reality (AR) applications to support individuals with special needs, such as intellectual disabilities, autism spectrum disorder, attention deficit hyperactivity disorder, and physical disabilities.
R. Baragash +3 more
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Specialusis Ugdymas, 2016 This paper attempts to highlight and examine the Romanian perspective regarding inclusive education by presenting some statistical data and the steps that have been made in order to make the switch from a school system lead by the segregation principle ...
Elena Marin
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Educação inclusiva em enfermagem: análise das necessidades de estudantes
Revista da Escola de Enfermagem da USPA educação inclusiva tem por base atender os alunos sem distinção, proporcionando uma educação voltada a todos, de forma a identificar as necessidades educacionais de qualquer aluno.
Ana Cristina Mancussi e Faro +1 more
doaj
Specialusis Ugdymas, 2019 This article examines relationships between the scores of Dyslexia Risk Questionnaire (DRQ) in preschool age and the abilities, necessary for acquisition of reading and writing skills, as well as reading and writing skills in the 1st Grade.
Katažyna Labanienė +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Journal of Orthopaedic Surgery and ResearchObjective This study examines whether cross-education training of the healthy limb promotes cross-transfer through central nervous system stimulation, enhancing the function, kinematic parameters, dynamic balance, and plantar pressure of the affected ...
Chao Liu +5 more
doaj +1 more source