Results 81 to 90 of about 69,764 (234)

Magnetic‐Guided Delivery of Antisense Oligonucleotides for Targeted Transduction in Multiple Retinal Explant and Organoid Models

Advanced Science, EarlyView.
Magnetic field‐guided MNP@ATR‐ASO nanocomplexes facilitate the targeted delivery of ASOs to ganglion cells or photoreceptors within retinal explants, thereby enhancing the efficacy of ASOs in correcting pre‐mRNA splicing abnormalities. Furthermore, the nanocomplexes improve ASO penetration and delivery in human retinal and inner ear organoid models ...
Xiuhong Ye, Sihui Chen, Wei Xiong, Fan Wang, Hon Fai Chan, Haocheng Lai, Xiangyu Guo, Tingting Yang, Shuhao Shen, Hang Chen, Wenxuan Wang, Guei‐Sheung Liu, Yonglong Guo, Jiansu Chen   +13 more
wiley   +1 more source

Altruism in death: Attitudes to body and organ donation in Australian students

Anatomical Sciences Education, Volume 16, Issue 1, Page 27-46, January/February 2023., 2023
Abstract Health education, research, and training rely on the altruistic act of body donation for the supply of cadavers. Organ transplantation and research rely on donated organs. Supply of both is limited, with further restrictions in Australia due to requirements for a next‐of‐kin agreement to donation, irrespective of the deceased's pre‐death ...
Rebekah A. Jenkin, Samuel A. Garrett, Kevin A. Keay   +2 more
wiley   +1 more source

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

Advanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao, Chao Yan, Haibo Huang, Shilong Wang, Jiaying Li, Yun Chen, Xiaolu Qu, Qi Bao, Lingna Xu, Yuanyuan Zhang, Danyang Fan, Xia He, Yanwen Liu, Yongsheng Zhang, Yalan Yang, Zhonglin Tang   +15 more
wiley   +1 more source

Dyad pedagogy in practical anatomy: A description of the implementation and student perceptions of an adaptive approach to cadaveric teaching

Anatomical Sciences Education, Volume 16, Issue 1, Page 99-115, January/February 2023., 2023
Abstract Prior to the challenges imposed by the Covid‐19 pandemic, anatomy practical sessions at Trinity College Dublin involved eight to 10 students per donor station, rotating between digital learning, anatomical models/osteology, and dissection activities for three hours weekly.
Dearbhla P. Cullinane, Denis S. Barry
wiley   +1 more source

Veterinary Students’ Perceptions of Entrepreneurship Education

Proceedings
In this study, the opinions and perceptions of students at a school of veterinary medicine regarding the importance of entrepreneurship education in modern higher education are investigated.
Georgia Koutouzidou, Vagis Samathrakis, Athanasios Batzios, Alexandros Theodoridis   +3 more
doaj   +1 more source

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin, Hongchao Gou, Xiaoyun Qu, Kaiyuan Jia, Yuhui Deng, Dan Li, Qianyi Cai, Yucen Liang, Xiaozhen Xu, Yanbin Li, Jianhan Lin, Letian Li, Yuhang Jiang, Shouwen Du, Lingcong Deng, Bailing Yan, Ruidong Liu, Chang Li, Jianmin Zhang, Ming Liao   +19 more
wiley   +1 more source

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

Advanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu, Jeffrey Galley, Jason Pizzini, Elena Musteata, Martin V. Douglas, Walter J. Chazin, Eric P. Skaar, Jeffrey J. Tabor, Robert A. Britton   +8 more
wiley   +1 more source

The Effect of Pore Functionality in Multicomponent Covalent Organic Frameworks on Stable Long‐Term Photocatalytic H2 Production

Advanced Energy Materials, EarlyView.
Five COFs are synthesized through a multicomponent reaction, preserving a similar backbone while introducing varying pore functionalities. All COFs demonstrate excellent chemical stability and sustained H2 production under sunlight for 7‐15 days. The imidazole‐functionalized COF exhibits the highest H2 production, which can be attributed to its high ...
Prasenjit Das, Gouri Chakraborty, Jin Yang, Jérôme Roeser, Hüseyin Küçükkeçeci, Anh Dung Nguyen, Michael Schwarze, Jose Gabriel, Christopher Penschke, Shengjun Du, Vincent Weigelt, Islam E. Khalil, Johannes Schmidt, Peter Saalfrank, Martin Oschatz, Jabor Rabeah, Reinhard Schomäcker, Franziska Emmerling, Arne Thomas   +18 more
wiley   +1 more source

The role of intrinsic motivation and continuous enhancement on the intention to implement animal welfare practices in dairy farming

Applied Economic Perspectives and Policy, EarlyView.
Abstract Animal welfare programs alone are insufficient to ensure better welfare for farm animals. Effective farm management, driven by dairy farmers' intrinsic motivation, plays a pivotal role. This study examines the factors influencing dairy farmers' intention to implement animal welfare practices and their commitment to continuously enhancing ...
Henrike Grotsch, Marcus Mergenthaler, Sarah Kühl, Holger Schulze   +3 more
wiley   +1 more source

Are veterinary drug maximum residue limits protectionist? International evidence

Applied Economic Perspectives and Policy, EarlyView.
Abstract We analyze the distribution of maximum residue limits (MRLs) on veterinary drugs used in animal production and aquaculture in a global context of food consumption and trade. We compare MRLs by drug‐product pairs for a large set of countries, commodities, and drugs.
Akinbode Okunola, Elliott Dennis, John Beghin   +2 more
wiley   +1 more source