Results 21 to 30 of about 2,317 (272)
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan +7 more
wiley +1 more source
ABSTRACT Farmers markets provide a direct‐to‐consumer marketing path for farmers and small businesses, facilitating customer discovery and product refinement. This paper explores farmers markets as a business incubator, with a focus on beginning vendors and resilience to a shock, namely, COVID‐19 market restrictions.
Mallory L. Rahe +2 more
wiley +1 more source
The rain feels different under the same umbrella: Experiences with poverty across LGBTQ subgroups
Abstract Population‐based survey data have demonstrated that LGBTQ communities report varying rates of economic insecurity, yet very little research directly assesses how pathways into and experiences with poverty look different among subgroups at the intersections of sexual orientation and gender identity (SOGI).
Bianca D. M. Wilson, Lillian Nguyen
wiley +1 more source
The psychosocial toll of Dublin III on asylum seekers in the Netherlands
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley +1 more source
The association between dietary fatty acid intake and the development of atopic diseases has been inconsistent. This could be due to inter-individual genetic differences in fatty acid metabolism.The aim of the current study was to assess the influence of
Standl, M;Sausenthaler, S;Lattka, E;Koletzko, S;Bauer, CP;Wichmann, HE;von Berg, A;Berdel, D;Kramer, U;Schaaf, B;Röder, S;Herbarth, O;Klopp, N;Koletzko, B;Heinrich, J
core +2 more sources
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta +17 more
wiley +1 more source
The education quality model: Saudi and British perspectives on pillars of quality in education [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Research Purpose: This study aims to build a new model of quality for education based on a Saudi-British consensus regarding the major factors contributing ...
Abaalkhail, Mohammed
core
Modelling of tuna around fish aggregating devices: The importance of ocean flow and prey
Catch and distribution of tuna in the ocean are typically investigated with ocean basin-scale models. Due to their large scale, such models must greatly simplify tuna behaviour occurring at a scale below ∼100 km, despite interactions at this level ...
Nicol, Simon +9 more
core +1 more source

