Results 31 to 40 of about 1,017,767 (309)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

OBLIGATORY PROGRAM AND ITS EFFICACY IN PATIENTS WITH OSTEOARTHRITIS

Научно-практическая ревматология, 2001
The aim of the research was to create education programme and investigate its effict in patients with osteoarthritis. The programme included 9 subjects, concerning of main questions of osteoarthritis self-control.
S S Yakushin, S. P. Filonenko, N V Minayeva, N A Rondaleva   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Higher Education outreach to widen participation: toolkits for practitioners. Overview [PDF]

, 2013
The toolkits are a distillation of the learning, methods and resources developed by Aimhigher and the Lifelong Learning Network programmes to support the effective strategy, management and delivery of outreach work to encourage progression to higher ...
Dent, Phil, Garton, Elizabeth, Hooley, Tristram, Leonard, Christopher, Marriott, John, Moore, Nicki   +5 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A Biosocial Perspective to Understand Antimicrobial Prescription Practices: A Retrospective Cross-Sectional Study from a Public Community Health Center in North India

Antibiotics
Background: It is well established by research that large-scale and indiscriminate prescribing, dispensing, and use of antimicrobials drive antimicrobial resistance (AMR) endangering the health and well-being of people, animals, and the environment.
Rashmi Surial, Sundeep Sahay, Vinay Modgil, Arunima Mukherjee, Ritika Kondal Bhandari   +4 more
doaj   +1 more source

La littérature dans l’enseignement scolaire en Russie

Revue Internationale d’Éducation de Sèvres, 2012
In Russia, where literature is still a central feature, it is considered to be one of the main subjects of humanities, which must be studied by all pupils. Literature teaching at school is divided up into different levels depending on pupils’ age and the
Lioudmila Troubina, Viktor Chertov
doaj   +1 more source

Te Puni Rumaki – Strengthening Māori medium initial teacher education [PDF]

, 2014
The delivery of initial teacher education for Māori medium contexts in Aotearoa seeks to support the revitalization of the indigenous language and practices in collaboration with the current education system.
Hawera, Ngārewa, Heaton, S, Hohepa, Margie Kahukura, Tamatea, Karaitiana   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Curriculum, entre modèle rationnel et irrationalité des sociétés

Revue Internationale d’Éducation de Sèvres, 2011
The author demonstrates the complementary nature of two different approaches to the concept of curricula. The article includes a table showing a rational model of the concept of a curriculum.
Philippe Jonnaert
doaj   +1 more source