Results 41 to 50 of about 1,017,767 (309)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

COMPARATIVE STUDY OF ONGOING ADULT LEARNING IN PUBLIC SERVICES AND NON-PROFIT SECTOR (CASE STUDY)

open access: yesJournal on Efficiency and Responsibility in Education and Science, 2012
The aim of this paper is to compare the diversity of lifelong learning in public administration and non-profit sector and determine whether after 2009 there have been financial changes in the field of lifelong education of economically active population ...
VARVAŽOVSKÁ, Pavla   +1 more
doaj   +1 more source

Entre unité et diversité

open access: yesRevue Internationale d’Éducation de Sèvres, 2015
In Russia, history teaching today is confronting the traditional bipolar approach to national history, a confrontational vision of the world, the question of minorities and regional issues and the influence of administrative reforms on educational ...
Aleksei Kilin
doaj   +1 more source

Training them to catch fish? Farmer education and training programmes in Uganda’s organic agricultural subsector [PDF]

open access: yes, 2012
This policy brief explores the nature of training and education activities of civil society organisations and tertiary institutions in Uganda. An internet search of the training and education activities in organic agriculture in Uganda shows overwhelming
Pophiwa, Nedson
core  

An investigation into the comparative learning gain and ‘value added’ for students from widening participation and non-widening participation groups:a case study from sports degrees [PDF]

open access: yes, 2018
Increasingly universities are expected to demonstrate the impact of students’ higher education experiences; learning gain is one of the metrics that can evidence this.
Cameron, Andrea J.   +2 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Social and cultural determinants of antibiotics prescriptions: analysis from a public community health centre in North India

open access: yesFrontiers in Pharmacology
This paper explores the socio cultural and institutional determinants of irresponsible prescription and use of antibiotics which has implications for the rise and spread of antimicrobial resistance (AMR). This study describes the patterns of prescription
Arunima Mukherjee   +8 more
doaj   +1 more source

L’histoire scolaire en France

open access: yesRevue Internationale d’Éducation de Sèvres, 2015
History is a long-established discipline in schools in France. Since its creation it has been placed under the aegis of politics, making it subject to frequent polemics about what should be taught, and how.
Patricia Legris
doaj   +1 more source

Réformer avec et pour les jeunes

open access: yesRevue Internationale d’Éducation de Sèvres, 2020
Within the French-speaking world, young people, of whom there are many, want to take part in decisions concerning their economic and social life. Even if, at times, they express their desire in a very brutal way, it is encouraging to see young people ...
Ma-Umba Mabiala, Gisèle Menye Langue
doaj   +1 more source

L’oral au primaire en Côte d’Ivoire : entre normes communautaires et normes scolaires

open access: yesRevue Internationale d’Éducation de Sèvres, 2021
This study focuses on oral language in rural Ivorian primary schools, and rests on the premise that the teaching-learning of a language that is not that of learners’ first socialisation must adopt a perspective of mediation of meaning.
Bénédicte Techti
doaj   +1 more source

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