Results 31 to 40 of about 233,294 (316)

France : l’avancée du Socle commun et les questions posées

Revue Internationale d’Éducation de Sèvres, 2011
The French situation is analysed with reference to both the procedures inherent to the “content machine” and “products”, i.e. the teaching programmes in effect in 2011.
Roger-François Gauthier, Maryline Coquidé, Dominique Raulin   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A Biosocial Perspective to Understand Antimicrobial Prescription Practices: A Retrospective Cross-Sectional Study from a Public Community Health Center in North India

Antibiotics
Background: It is well established by research that large-scale and indiscriminate prescribing, dispensing, and use of antimicrobials drive antimicrobial resistance (AMR) endangering the health and well-being of people, animals, and the environment.
Rashmi Surial, Sundeep Sahay, Vinay Modgil, Arunima Mukherjee, Ritika Kondal Bhandari   +4 more
doaj   +1 more source

Une mise en perspective de l’éducation aux valeurs des droits de l’homme au Maroc

Revue Internationale d’Éducation de Sèvres, 2021
This study considers the relationship between education in the values of human rights, politics and pedagogy in Morocco since independence. The authors identify three periods in the evolution of human rights education: before 1992, a latency phase ...
Mostafa Hassani-Idrissi, Mohammed Zernine   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Taking ownership: The story of a successful partnership for change in a Pacific Island science teacher education setting.

, 2011
This paper explores an example of a partnership approach that appears to be producing sustainable change in a Pacific Islands education setting. The people involved report on the way science education staff from the Solomon Islands School of Education ...
Pita, Solomon, Solomon Pita, Porakari, James, Edwards, Richard, James Porakari, Richard Edwards   +5 more
core   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Introduction to special edition.

, 2010
This special issue of the Waikato Journal of Education arose from a symposium held at The University of Waikato in June, 2009. The symposium, Initial Teacher Education and the New Zealand Curriculum–Te Marautanga o Aotearoa Symposium, was attended by ...
Cooper, Beverley, McGee, Clive
core   +1 more source

Directives pédagogiques et soubassement idéologique

Revue Internationale d’Éducation de Sèvres, 2012
The author presents thoughts on three generations of textbooks for learning French, the language of education and administration in Senegal, from two points of view: historical and didactic.
Abdoulaye Elimane Kane
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source