Results 51 to 60 of about 1,017,767 (309)
Working towards integration: Advancing Care Coordination & TeleHealth Deployment (ACT) Programme [PDF]
, 2014 This poster gives a summary of the ACT Programme, the sites participating, diseases covered, numbers of patients, project timetable and the aim to provide a ‘toolbox’ of best practice.
Bescos, Cristina +2 more
core +4 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Frontiers in MicrobiologyIntroductionSustained and sub-optimal antimicrobial use drives antimicrobial resistance (AMR), a major health systems challenge in low- and middle-income countries (LMICs) such as India.
Vinay Modgil +11 more
doaj +1 more source
The promises of educational technology: a reassessment [PDF]
, 1986 The claims made for educational technology have not always been realized. Many programmes in education based on media and technology have produced useful documentation and supportive research; others have failed.
Ely, Donald P., Plomp, Tjeerd
core +3 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Conception et mise en œuvre du curriculum commun en France : avancées et limites
Revue Internationale d’Éducation de Sèvres, 2016 Michel Lussault, President of the Conseil Supérieur des Programmes (CSP, France) discusses on the innovations in curricular policies in France since 2013: the new importance afforded to “learning to learn” as well as moral considerations, open towards a ...
Michel Lussault
doaj +1 more source
Engineering programme structure requirements for Bologna compliance [PDF]
, 2007 In 1999 twenty nine European countries have signed the Bologna Declaration to establish a common European higher education system as for the year 2010. Engineering Ireland has decided that the education standard for the title of CEng and MIEI should be ...
Olabi, Abdul-Ghani
core
Investigating Educational Change: The Aga Khan University Institute For Educational Development Teacher Education For School Improvement Model [PDF]
, 2007 This article continues the analyses of the impact of an innovative teacher education programme aimed at school improvement in a developing country context (Khamis and Sammons 2004).
Khamis, Anil, Sammons, Pam
core +3 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source