Results 81 to 90 of about 1,041,912 (362)

Croatia: introducing and strengthening the non-university sector [PDF]

open access: yes, 2016
The report concerns Croatia's policy to strengthen its non-university higher education provision and increase horizontal differentiation among its higher education institutions and study programmes.
Brankovic, Jelena, Vukasovic, Martina
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

France : l’avancée du Socle commun et les questions posées

open access: yesRevue Internationale d’Éducation de Sèvres, 2011
The French situation is analysed with reference to both the procedures inherent to the “content machine” and “products”, i.e. the teaching programmes in effect in 2011.
Roger-François Gauthier   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

A comparison of the effectiveness of three parenting programmes in improving parenting skills, parent mental-well being and children's behaviour when implemented on a large scale in community settings in 18 English local authorities : the parenting early intervention pathfinder (PEIP) [PDF]

open access: yes, 2011
Background There is growing evidence that parenting programmes can improve parenting skills and thereby the behaviour of children exhibiting or at risk of developing antisocial behaviour.
Davis, Hilton   +2 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Editorial [PDF]

open access: yes, 2011
An introduction is presented in which the editor discusses various reports within the issue on topics including the sustainability of organisational changes for diploma programmes, the development of Preparation for Tertiary Learning (PTL), and childhood
Strachan, Jane, Wright, Noeline
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Directives pédagogiques et soubassement idéologique

open access: yesRevue Internationale d’Éducation de Sèvres, 2012
The author presents thoughts on three generations of textbooks for learning French, the language of education and administration in Senegal, from two points of view: historical and didactic.
Abdoulaye Elimane Kane
doaj   +1 more source

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