Results 61 to 70 of about 4,482,722 (250)

Education and Solidarity: A Path towards Educational Inclusion

Historia Social y de la Educación, 2020
Educational inclusion is a process that is immersed in the everyday life of Colombians and that demands of each citizen a significant contribution to make this possible; for this reason, this article aims to review the existing literature on education ...
Isabel Hernandez Arteaga, Karen Margarita Fernandez Lopez, Alejandra Corina Estela Vasquez, Edith Johanna Mestizo Nuzcue   +3 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Caracterização dos professores itinerantes, suas ações na área de tecnologia assistiva e seu papel como agente de inclusão escolar Characterization of itinerant teachers, their work in assistive technology, and their role as inclusion agents

Revista Brasileira de Educação Especial, 2009
O presente estudo discute o trabalho do professor itinerante dentro da Secretaria Municipal de Educação do município do Rio de Janeiro. Compara a ação desses profissionais junto aos alunos com necessidades educacionais especiais incluídos nas escolas ...
Miryam Bonadiu Pelosi, Leila Regina d'Oliveira de Paula Nunes   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The educational placement of children with autism: what do parents think? [PDF]

, 2001
Plan BThis study attempted to investigate the parental perceptions of inclusive placements of their autistic children. There were three main questions this study wished to answer: how parents felt about inclusion, the major benefits and drawbacks of ...
Mattingly, Lisa-Marie
core  

Análise da necessidade de preparação pedagógica de professores de cursos de licenciatura para inclusão de alunos com necessidades educacionais especiais Analysis of the need for a bachelor degree professors' pedagogical preparation to deal with the special need students' inclusion

Revista Brasileira de Educação Especial, 2007
A inclusão de alunos com necessidades educacionais especiais (NEE) requer professores capazes de promover sua aprendizagem e participação. No entanto, a maioria dos professores atuantes nos diversos níveis de ensino se encontra despreparada para assumir ...
Célia Regina Vitalino
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The effects of inclusion on general education students [PDF]

, 2001
Plan BThe purpose of this study was to examine the effects that inclusion of special education students have on regular education students. This was done through a comprehensive review and critical analysis of research and literature concerning both ...
Pawlowicz, Bruce
core