Results 61 to 70 of about 205,214 (289)

After Warnock: The Effects of Perverse Incentives in Policies in England for Students With Special Educational Needs

Frontiers in Education, 2019
The 1978 Warnock Report made the case in the United Kingdom for a number of actions that, it was argued, would make the integration and support of young people with Special Educational Needs more effective.
Harry Daniels, Ian Thompson, Alice Tawell   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

La Inclusión Educativa. Reflexiones y Propuestas entre las Reflexiones, las Demandas y los Slogans

Revista Iberoamericana sobre Calidad, Eficacia y Cambio en Educación, 2016
Se analiza la cuestión de la inclusión educativa desde una postura a la vez analítica y propositiva. El itinerario argumentativo del trabaja atraviesa los problemas de enunciación de los asuntos vinculados al par inclusión-exclusión, el esbozo de un ...
Mariano Naradowski
doaj  

Projetos Socioeducativos: a naturalização da exclusão nos discursos de educadores

Sociedade e Estado, 2010
O artigo aborda a temática da exclusão/inclusão em práticas de educação não escolar, a partir dos discursos de educadores que atuam em projetos socioeducativos voltados a crianças e jovens, moradores de periferias urbanas.
Dinora Tereza Zucchetti, Eliana Perez Gonçalves de Moura, Magali Mendes de Menezes   +2 more
doaj   +1 more source

“He’s shouting so loud but nobody’s hearing him”: A multi-informant study of autistic pupils’ experiences of school non-attendance and exclusion

Autism and Developmental Language Impairments, 2023
Background and aims Children and young people on the autism spectrum frequently report a range of negative educational experiences and face disproportionally high rates of school non-attendance, including school avoidance and permanent exclusion, which ...
Laura Gray, Vivian Hill, Elizabeth Pellicano   +2 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Édito - L’éducation inclusive en contexte de diversité ethnoculturelle : comprendre les processus d’exclusion pour agir sur le terrain de l’école

Recherches en Éducation, 2021
Marie-Odile Magnan, Justine Gosselin-Gagné, Geneviève Audet, Xavier Conus   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

‘From Integration to Inclusive Education in England: Illuminating the Issues Through A Life History Account’ [PDF]

, 2014
This paper provides a life history account of one teacher’s determination to make inclusion work. The account reflects on the policy discourses of integration and inclusion and demonstrates ways in which these were translated into practice within ...
Glazzard, Jonathan
core   +3 more sources