Results 81 to 90 of about 2,232,862 (290)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Geophysical Fluid Dynamics Laboratory [PDF]
Located in Princeton, New Jersey, GFDL conducts research where the goal is to expand the scientific understanding of the physical processes that govern the behavior of the atmosphere and the oceans as complex fluid systems.
core +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Investigating Educational Change: The Aga Khan University Institute For Educational Development Teacher Education For School Improvement Model [PDF]
, 2007 This article continues the analyses of the impact of an innovative teacher education programme aimed at school improvement in a developing country context (Khamis and Sammons 2004).
Khamis, Anil, Sammons, Pam
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Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
A Systematic Review of Co-Educational Models in School Handball. [PDF]
Int J Environ Res Public Health, 2021 Arias AR, Soto D, Ferreira C.
europepmc +1 more source
Intergenerational Educational Transmission within Families: An Analysis and Microsimulation Projection for Austria [PDF]
In this contribution we study intergenerational educational transmission within families in Austria. The paper is divided into an analytical part and a synthesis of the resulting behavioural models to a comprehensive computer microsimulation model that ...
Martin Spielauer
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Adjustment and Completion of BASNEF Model to Provide a New Model for Educating Large Populations in Relation to Cutaneous Leishmaniasis [PDF]
, 2014 Background: Educational models that have been created for educating small populations do not have enough efficacy for educating large populations, so based on this premise and also high prevalence of Cutaneous Leishmaniasis (CL) in the Islamic Republic
Behravesh, O. +5 more
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Older adult education in a Maltese University of the Third Age : a critical perspective [PDF]
, 2000 The education of older adults has been considered the fastest growing branch of adult education in post-industrial countries and one of the most crucial challenges facing current adult European education. It has generated a significant number of research
Formosa, Marvin
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source