Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
Minutes: Educational Policy Committee, September 12, 2001
University of Minnesota Duluth. Educational Policy Committee. (2001). Minutes: Educational Policy Committee, September 12, 2001.
University of Minnesota Duluth. Educational Policy Committee
core
Post-implementation knowledge retention of stroke: the lasting influence of FAST Heroes
BackgroundFAST Heroes is a kindergarten-based educational program that teaches young children and their extended families (parents, grandparents), the main stroke symptoms (Face, Arm, and Speech), and the timely and appropriate steps in the event of a ...
Emilia Orologa +5 more
doaj +1 more source
Austerity and inequality; or prosperity for all? Educational policy directions beyond the pandemic. [PDF]
Hargreaves A.
europepmc +1 more source
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng +10 more
wiley +1 more source
Minutes: Educational Policy Committee, January 28, 2009
University of Minnesota Duluth. Educational Policy Committee. (2009). Minutes: Educational Policy Committee, January 28, 2009.
University of Minnesota Duluth. Educational Policy Committee
core
Classroom Placement and Twins' Social Behaviors in Elementary School: Providing Empirical Evidence to Inform Educational Policy. [PDF]
Garon-Carrier G +6 more
europepmc +1 more source
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar +10 more
wiley +1 more source
Minutes: Educational Policy Committee, April 29, 1998
University of Minnesota, Duluth. Educational Policy Committee. (1998). Minutes: Educational Policy Committee, April 29, 1998.
University of Minnesota, Duluth. Educational Policy Committee
core
Effect of cognitive behavioral active engagement training on test item construction skills among primary school teachers in Nigeria: Implication for educational policy makers. [PDF]
Ede MO +10 more
europepmc +1 more source

