Results 61 to 70 of about 68,155,158 (246)

La gestión de la Ciencia e Innovación y la formación doctoral en Cuba. Experiencias en las ciencias de la educación.

open access: yesTeuken Bidikay, Revista Latinoamericana de Investigación en Organizaciones Ambiente y Sociedad, 2020
El artículo presenta las experiencias en la dirección de un proyecto de investigación para la educación ambiental en las instituciones educativas de las montañas del centro de Cuba.
Gonzalo González Hernández
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Una propuesta metodológica para la realización de búsquedas sistemáticas de bibliografía (A methodological proposal for the systematic literature review)

open access: yesWPOM : Working Papers on Operations Management, 2010
El presente trabajo pretende ser una guía para la realización de búsquedas sistemáticas de bibliografía que sirvan para conocer en profundidad un determinado campo de estudio, desarrollar un marco teórico y establecer las hipótesis adecuadas sobre las ...
Carmen Medina-Lopez   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

L’approche phénoménologique en sciences de l’éducation : quels apports méthodologiques ?

open access: yesRecherches en Éducation
This article presents an analysis of some of the empirical data from two studies of teaching-learning situations in elementary schools. Educational situations are complex and need to be explored using a variety of approaches if they are not to be reduced
Caroline Baugey, Marie Gabriel
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Qualitative Content Analysis: Disciplinary Perspectives and Relationships between Methods—Introduction to the FQS Special Issue "Qualitative Content Analysis II"

open access: yesForum: Qualitative Social Research, 2020
In this article, we introduce Part II of the special issue on qualitative content analysis (QCA). To begin with, we provide a short summary of the rationale underlying both parts of the special issue and present some core conclusions based on Part I ...
Margrit Schreier   +4 more
doaj   +1 more source

Observations on European Education and Educational Research: The European Educational Research Journal at work 2002-2014

open access: yes, 2014
This is a review of the European Educational Research Journal since the start in 2002 and up to 2014. Three questions were put forwards: what are the ambitions with the journal, how has the journal developed over time, and what are its possible futures ...
Lindblad, Sverker,
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Editorial : Posthuman Conceptions of Change in Empirical Educational Research

open access: yes, 2021
In this special issue of Reconceptualizing Educational Research Methodology the focus is on posthuman conceptions of change in empirical educational research.
Bodén, Linnea   +7 more
core   +1 more source

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