Results 61 to 70 of about 7,863,333 (293)

Ownership and Usage of Mobile Devices Among Ophthalmology Residents and Attending Physicians: Identifying the Generation Gap

Advances in Medical Education and Practice, 2020
Adi Mohammed Al Owaifeer,1,2 Abdulaziz Al Taisan,1 Bader Alqahtani,3 Khalid Alburayk,4 Majed Alsubaie,5 Saad H Alenezi6 1Faculty of Ophthalmology, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia; 2King Khaled Eye Specialist Hospital ...
Al Owaifeer AM, Al Taisan A, Alqahtani B, Alburayk K, Alsubaie M, Alenezi SH   +5 more
doaj  

Fonctionnements et trajectoires des réseaux professionnels en ligne : le cas des réseaux d’enseignants

Distances et Médiations des Savoirs, 2014
Digital technologies facilitate the creation of networks focused on connecting people. They allow users to create, mix and easily share informative contents and therefore support the development of on-line networks with the objective of sharing knowledge
Isabelle Quentin
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Enseñanza y difusión sobre el uso de recursos educativos abiertos con MOOC: un estudio de caso

CPU-e, 2018
El presente artículo analiza el caso de un Curso en Línea Masivo y Abierto (MOOC) que tiene por objetivo desarrollar competencias digitales y de diseño instruccional para integrar Recursos Educativos Abiertos (REA) en ambientes de aprendizaje. Se utiliza
Martín Alonso Mercado Varela, Katiuska Fernández Morales, Gilles Lavigne, María Soledad Ramírez Montoya   +3 more
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Nursing students’ experiences with the “DiagNurse” mobile app to support clinical patient assessment – a pilot study

Pielęgniarstwo XXI Wieku
NURSING STUDENTS’ EXPERIENCES WITH THE “DIAGNURSE” MOBILE APP TO SUPPORT CLINICAL PATIENT ASSESSMENT – A PILOT STUDY Aim. This study aimed to investigate how nursing students utilised the “DiagNurse” mobile app to assess patient health conditions ...
Barbara Ślusarska, Agnieszka Chrzan-Rodak, Aneta Bernadeta Jędrzejewska, Monika Bieniak-Czerepak, Wiktoria Mazurek, Alicja Waśkowicz, Grzegorz Józef Nowicki   +6 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Open Educational Resources: The Way Forward [PDF]

, 2008
The report, "Open Educational Resources: The Way Forward", presents the results of an extensive international consultation to identify an agenda for advancing the Open Educational Resources (OER) movement worldwide.
Susan D'Antoni
core   +1 more source

Differentiation in Access to, and the Use and Sharing of (Open) Educational Resources among Students and Lecturers at Kenyan Universities

Open Praxis, 2017
In order to obtain a fair ‘OER picture’ for the Global South a large-scale study has been carried out for a series of countries, including Kenya. In this paper we report on the Kenya study, run at four universities that have been selected with randomly ...
Judith Pete, Fred Mulder, Jose Dutra Oliveira Neto   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source