Results 61 to 70 of about 14,504,087 (298)

Opportune and inopportune expectations from the philosophy of education [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2006
During the past centuries, the knowledge itself, which had expanded with the aim of discovering the truth about the universe, was very important. This attitude was changed in the twentieth century especially in its second half.
Isaa Ebrahimzadeh
doaj  

Redefining Science Education [PDF]

open access: yesScience, 2009
There is a major mismatch between opportunity and action in most education systems today. It revolves around what is meant by "science education," a term that is incorrectly defined in current usage. Rather than learning how to think scientifically, students are generally being told about science and asked to remember facts.
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Student factors that difficult teaching-learning of research skills

open access: yesInteracciones, 2017
The aim of this study was to describe the teachers and students perspective of an educational science center belonging to a public university in Mexico, about factors associated with students, which hinder the teaching-learning process of research skills.
Yamile Andrea Gómez-Delgado   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Conceptions de la recherche des universitaires de sciences de l’éducation et formes des travaux émergents

open access: yesÉducation et Socialisation, 2011
On the basis of a theoretical approach of the scientific activity, which insists on the process of evaluation and construction by the peers of the quality of emergent research, this article aims at delimiting the frames of reference from which emergent ...
Daniel Bart
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Educational sciences research papers

open access: yes, 2019
Educational Sciences Research ...
Sert , Meral Ağır   +1 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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