Results 81 to 90 of about 14,504,087 (298)
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Network meta-analysis in psychology and educational sciences: A systematic review of their characteristics. [PDF]
Fernández-Castilla B +1 more
europepmc +1 more source
Inquiry has played a major role in the past and present science education reforms around the world. Despite a great number of studies leveraging TIMSS and PISA data to investigate inquiry in science education, there is little effort to synthesize their findings.
openaire +2 more sources
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Metacognition: ideas and insights from neuro- and educational sciences. [PDF]
Fleur DS, Bredeweg B, van den Bos W.
europepmc +1 more source
Collective Review: Three Approaches to Teaching and Learning Metaphors
Reflecting on the guiding force of metaphors is a long-standing tradition in the German-speaking educational sciences. However, no connection is made to the theory of metaphor, which is derived from modern cognitive linguistics.
Rudolf Schmitt
doaj
Thematic Content Analysis of Studies Using Generalizability Theory
Oneof the important theories in education and psychology is Generalizability (G)Theory and various properties distinguish it from the other measurementtheories.
Gülşen Taşdelen Teker, Neşe Güler
doaj +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Data Envelopment Analysis (DEA) in the Educational Sciences. [PDF]
Shero JA +3 more
europepmc +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source

