Results 91 to 100 of about 14,504,087 (298)
Content analysis of defended master theses at the Faculty of Educational Sciences in Sarajevo, Bosnia and Herzegovina [PDF]
Multidisciplinarni Pristupi u Edukaciji i RehabilitacijiCurrent trends in educational sciences can best be evaluated by assessing the master and doctoral theses defended at the universities. The goal of the present paper was to do a qualitative content analysis of the titles of master theses defended at the ...
Irma Čehić, Haris Memišević
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
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Frontiers in EducationGlobally, increasing numbers of individuals enter the teaching profession through alternative teacher education programs without prior university studies in teacher education or pedagogy.
Jonas Weyers +4 more
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FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Prioritizing Science Education [PDF]
Science, 2010 This special issue of Science explores “Grand Challenges in Science Education,” a critical set of the problems and exciting opportunities now facing science education on a global level. The 20 Challenges, addressed by a team of education experts, range from “Enable students to build on their own enduring, science ...
openaire +4 more sources
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Investigating the Teaching of Research Methodology in Psychology and Education in Iran [PDF]
فصلنامه نوآوریهای آموزشی, 2007 The preparation of this article is based on studies and findings of a scientifically approved research, which took place for “investigating research methodology in psychology and education in Iran.” The research questions to be investigated were as ...
Hossein Lotfabadi +2 more
doaj
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source