Results 41 to 50 of about 316,904 (267)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

THE Sociology of Educational Technology

open access: yesSakarya Üniversitesi Eğitim Fakültesi Dergisi, 2014
.
Ahmet Eskicumalı
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Brain Activities and Educational Technology

open access: yesSakarya Üniversitesi Eğitim Fakültesi Dergisi, 2014
.
Emel Rıza
doaj  

Educational technology integration project in Algeria

open access: yesCybrarians Journal, 2011
If we look at the project to integrate information and communications technology into the education sector, we find that the practical methodology for implementing this project is based on three basic problems: The problem of use by both components ...
Hend Ulwy
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

New educational technology in university

open access: yesPolylinguality and Transcultural Practices, 2014
The article is devoted to consideration of the two new educational technologies at the University. This quantization of texts and the supertest.
V S Avanesov
doaj  

A Way to Learn How to Design Educational Software [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2004
The improvement in the quality of instructional process stimulates the development of active teaching methods based on "learning by doing" principles. This paper shows an experience developed on educational informatics course to engineering instructors ...
Dalia M. Gil, Miguel A. Garay
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy