Results 81 to 90 of about 2,459,375 (309)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Aesthetic Mediation: The Formation of Practitioner–Researcher–Scholar Identity and Artistry in HE-Supported Vocational Research

open access: yesEducation Sciences
The failure of top-down approaches to education policy in England draws attention to the importance of context and foregrounds the need to help teachers to see themselves as practitioner–researchers, scholars and researchers capable of conducting ...
Daniel Gregson
doaj   +1 more source

Putting Sylvia in her place: Ashton-Warner as New Zealand educational theorist [PDF]

open access: yes, 2009
Sylvia Ashton-Warner, a New Zealand teacher, won international acclaim in the 1950s-1950s with her novels, autobiographies, and accounts of her educational theory. Blurring genres between fiction and autobiography, much of her writing was centred on the ‘
Middleton, Sue
core   +1 more source

The Necessity and Violence of Theory [PDF]

open access: yes, 2006
This paper offers a personal view of the need for and uses of theory in educational research. It draws on the work of two exemplary theorists to point up the epistemological role of theory in making research possible and making it reflexive.
Ball, Stephen
core   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

The Social Making of Educational Theory: Unraveling How to Understand the Content, Emergence, and Transformation of Educational Theory

open access: yesNordic Journal of Educational History, 2014
This article discusses the study of educational theories and ideas. Based on analyses of primarily the Danish scene, positing similarities with the other Nordic countries, we identify and investigate three main and today dominating approaches: a ...
Christian Sandbjerg Hansen, Trine Øland
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Andragogy in Practice: Applying a Theoretical Framework to Team Science Training in Biomedical Research

open access: yesBritish Journal of Biomedical Science
This study is the first to apply the theoretical principles of Malcolm Knowles’ theory of andragogy to evaluate data collected from learners who participated in team science training workshops in a biomedical research setting. Briefly, andragogy includes
Jacqueline M. Knapke   +11 more
doaj   +1 more source

Reconstructed grounded theory: beyond comparison? [PDF]

open access: yes, 2010
This paper examines the modifications made to constructed grounded theory for application within an ethnographic study of group work processes in a virtual learning environment.
Bradley, S. A.
core  

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