Dysregulation of Cytosolic c-di-GMP in Edwardsiella piscicida Promotes Cellular Non-Canonical Ferroptosis [PDF]
Programmed cell death plays an important role in modulating host immune defense and pathogen infection. Ferroptosis is a type of inflammatory cell death induced by intracellular iron-dependent accumulation of toxic lipid peroxides.
Ying Wen +10 more
doaj +2 more sources
Silver nitrate enhances antibacterial effect of colistin against intrinsic colistin resistant Edwardsiella piscicida [PDF]
Edwardsiella piscicida (E. piscicida) has been recognized as an important bacterial pathogen affecting fish, and it is also intrinsically resistant to colistin. E.
Yangbin Shi +7 more
doaj +2 more sources
Development of a real-time recombinase-aided amplification assay for rapid and sensitive detection of Edwardsiella piscicida [PDF]
Edwardsiella piscicida, a significant intracellular pathogen, is widely distributed in aquatic environments and causes systemic infection in various species.
Yuchen Dong +4 more
doaj +2 more sources
To date, four species of the genus Edwardsiella—E. tarda, E. ictaluri, E. piscicida, and E. anguilarum—have been identified as the cause of disease and mortality in various fish species.
Janneke Allaart +6 more
doaj +2 more sources
Identification and Characterization of EvpQ, a Novel T6SS Effector Encoded on a Mobile Genetic Element in Edwardsiella piscicida [PDF]
In this study, a hypothetical protein (ORF02740) secreted by Edwardsiella piscicida was identified. We renamed the ORF02740 protein as EvpQ, which is encoded by a mobile genetic element (MGE) in E. piscicida genome.
Duan You Li +11 more
doaj +2 more sources
The Zebrafish Antiapoptotic Protein BIRC2 Promotes Edwardsiella piscicida Infection by Inhibiting Caspases and Accumulating p53 in a p53 Transcription-Dependent and -Independent Manner [PDF]
IAPs (inhibitors of apoptosis) are endogenous caspase inhibitors with multiple biological activities. In the present study, we show functional characteristics of antiapoptotic protein BIRC2 (cIAP1) in response to Edwardsiella piscicida infection ...
Lu Cao +8 more
doaj +2 more sources
Edwardsiella piscicida, a facultative aerobic pathogen belonging to the Enterobacteriaceae family, is the etiological agent of edwardsiellosis that causes significant economic loses in the aquaculture industry.
Peng Zhou +8 more
doaj +2 more sources
HutZ is required for biofilm formation and contributes to the pathogenicity of Edwardsiella piscicida [PDF]
Edwardsiella piscicida is a severe fish pathogen. Haem utilization systems play an important role in bacterial adversity adaptation and pathogenicity. In this study, a speculative haem utilization protein, HutZEp, was characterized in E. piscicida.
Yan-Jie Shi +4 more
doaj +4 more sources
It is important that bacterium can coordinately deliver several effectors into host cells to disturb the cellular progress during infection, however, the precise role of effectors in host cell cytosol remains to be resolved.
Dahai Yang +11 more
doaj +2 more sources
Edwardsiella piscicida (E. piscicida) is one of the main pathogens of fish, which could invade the host through the gut. Glucose 6-phosphate (Glu6P) within the gut provides environmental stresses that affect the pathogenicity of bacteria.
Jinyu Liu +5 more
doaj +3 more sources

