Results 11 to 20 of about 537,505 (139)

The Developmental and Functional Implications of Age-Associated B Cells (ABCs) Across Tissue Microenvironments. [PDF]

Immunol Rev
ABSTRACT Age‐associated B cells (ABCs) are a dynamic B cell subset whose identity, development, and function are fundamentally shaped by the tissue microenvironments in which they reside. Primarily defined by expression of CD11c and T‐bet, ABCs arise across diverse contexts, including aging, infection, autoimmunity, and cancer, yet exhibit striking ...
Francis RL, Weinstein JS.
europepmc   +2 more sources

Parallel re-modeling of EF-1α function: divergent EF-1α genes co-occur with EFL genes in diverse distantly related eukaryotes [PDF]

, 2013
Background: Elongation factor-1α (EF-1α) and elongation factor-like (EFL) proteins are functionally homologous to one another, and are core components of the eukaryotic translation machinery. The patchy distribution of the two elongation
Inagaki, Yuji, Simpson, Alastair G. B., Sako, Yoshihiko, Heiss, Aaron A., Simpson, Alastair G., Nishimura, Yuki, Gawryluk, Ryan, Hashimoto, Tetsuo, Kamikawa, Ryoma, Yubuki, Naoji, Roger, Andrew J., Brown, Matthew W.   +11 more
core   +1 more source

Complex distribution of EFL and EF-1α proteins in the green algal lineage [PDF]

, 2007
Background EFL (or elongation factor-like) is a member of the translation superfamily of GTPase proteins. It is restricted to eukaryotes, where it is found in a punctate distribution that is almost mutually exclusive with elongation factor-1 alpha (EF-1α)
Keeling Patrick J, Rogers Matthew B, Patrick J Keeling, Matthew B Rogers, Noble Geoffrey P, Geoffrey P Noble, Noble, Geoffrey P., Rogers, Matthew B., Keeling, Patrick J. (Patrick John), 1969-   +8 more
core   +1 more source

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α [PDF]

, 2007
Activation of AMP-activated kinase (AMPK) in skeletal muscle increases glucose uptake, fatty acid oxidation, and mitochondrial biogenesis by increasing gene expression in these pathways.
B. M. Spiegelman, S. Jager, C. Handschin, Handschin, C., St-Pierre, J., J. St.-Pierre, Spiegelman, B. M., Jager, S.   +7 more
core   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +2 more sources

Stable transformation of Babesia bigemina and Babesia bovis using a single transfection plasmid [PDF]

, 2018
Babesia bigemina and Babesia bovis, are the two major causes of bovine babesiosis, a global neglected disease in need of improved methods of control.
Monica L. Mazuz, Marta G. Silva, Donald P. Knowles, Cooke, Brian M., Silva, Marta G., Mazuz, Monica L., Carlos E. Suarez, Brian M. Cooke, Suarez, Carlos E., Knowles, Donald P.   +9 more
core   +1 more source

Complex coordination of cell plasticity by a PGC-1α-controlled transcriptional network in skeletal muscle [PDF]

, 2015
Skeletal muscle cells exhibit an enormous plastic capacity in order to adapt to external stimuli. Even though our overall understanding of the molecular mechanisms that underlie phenotypic changes in skeletal muscle cells remains poor, several factors ...
Handschin, Christoph, Christoph Handschin, Kupr, Barbara, Barbara eKupr, Christoph eHandschin, Barbara Kupr, Handschin C, Kupr B   +7 more
core   +1 more source

EF-1α matrix

, 2016
The nuclear EF-1α alignment in fasta ...
Sereina Rutschmann (3201123), Michel Sartori (351489), Michael T. Monaghan (351491), Monaghan, Michael T., Rutschmann, Sereina, Vuataz, Laurent, Sartori, Michel, Laurent Vuataz (351488)   +7 more
core   +1 more source

EF-1α MrBayes tree file

, 2016
The nuclear EF-1α MrBayes output ...
Sereina Rutschmann (3201123), Michel Sartori (351489), Michael T. Monaghan (351491), Monaghan, Michael T., Rutschmann, Sereina, Vuataz, Laurent, Sartori, Michel, Laurent Vuataz (351488)   +7 more
core   +1 more source

EF-1α *BEAST tree file

, 2016
The nuclear EF-1α *BEAST output ...
Sereina Rutschmann (3201123), Michel Sartori (351489), Michael T. Monaghan (351491), Monaghan, Michael T., Rutschmann, Sereina, Vuataz, Laurent, Sartori, Michel, Laurent Vuataz (351488)   +7 more
core   +1 more source