Results 61 to 70 of about 20,043 (161)

Role of efavirenz plasma concentrations on long-term HIV suppression and immune restoration in HIV-infected children.

PLoS ONE, 2019
BackgroundTo access the long term relationship between efavirenz plasma concentrations and evolution of HIV RNA loads and CD4 cell counts in children.MethodsRetrospective analysis of data from HIV-infected children on first line efavirenz-containing ...
Nontiya Homkham, Tim R Cressey, Naim Bouazza, Lily Ingsrisawang, Pornchai Techakunakorn, Jutarat Mekmullica, Thitiporn Borkird, Achara Puangsombat, Sathaporn Na-Rajsima, Jean Marc Treluyer, Saik Urien, Gonzague Jourdain   +11 more
doaj   +1 more source

A Physiologically-Based Pharmacokinetic Simulation to Evaluate Approaches to Mitigate Efavirenz-Induced Decrease in Levonorgestrel Exposure with a Contraceptive Implant

Pharmaceutics
Background: Levonorgestrel implant is a highly effective hormonal contraceptive, but its efficacy may be compromised when used with cytochrome enzyme inducers such as efavirenz. The primary aim of this study was to evaluate methods of mitigating the drug
Lilian W. Adeojo, Rena C. Patel, Nancy C. Sambol   +2 more
doaj   +1 more source

Perbandingan Penggunaan Efavirenz dan Nevirapine Terhadap Kolesterol LDL Pasien HIV/AIDS

Pharmaceutical Sciences and Research, 2019
Gangguan metabolik lipid merupakan kondisi yang sering ditemukan pada pasien HIV (Human Immunodeficiency Virus)/AIDS (Acquired Immuno Deficiency Syndrome) pada pasien yang menggunakan antiretroviral (ARV) lini pertama seperti efavirenz dan nevirapine ...
Anggriani Yusi, Evy Yunihastuti, Yulia Trisna, Ade Rosanti, Reise Manninda, Rifka Annisa   +5 more
doaj   +1 more source

Interaction and compatibility studies of efavirenz with pharmaceutical excipients

Journal of Excipients and Food Chemicals, 2016
Although excipients have traditionally been thought of as being inert, experience has shown that there can be interactions between excipients and drugs. Thus, knowledge of potential physical and chemical interactions can be very useful. The compatibility
Cinira Fandaruff, Andrea Mariela Araya-Sibaja, Rafael Nicolay Pereira, Silvia Lucia Cuffini, Carlos Eduardo Maduro de Campos, Cristiane Rodrigues Drago Hoffmeister, Helvécio Vinícius Antunes Rocha, Marco Antônio Segatto Silva   +7 more
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Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients.

PLoS ONE, 2011
BackgroundImplication of pharmacogenetic variations and efavirenz pharmacokinetics in concomitant efavirenz based antiviral therapy and anti-tubercular drug induced liver injury (DILI) has not been yet studied.
Getnet Yimer, Nobuhisa Ueda, Abiy Habtewold, Wondwossen Amogne, Akira Suda, Klaus-Dieter Riedel, Jürgen Burhenne, Getachew Aderaye, Lars Lindquist, Eyasu Makonnen, Eleni Aklillu   +10 more
doaj   +1 more source

Development and validation of a HPLC analytical assay method for efavirenz tablets: a medicine for HIV infections

Brazilian Journal of Pharmaceutical Sciences, 2011
Efavirenz is a reverse transcriptase non analog nucleoside inhibitor used to treat HIV infections. A simple assay method by high performance liquid chromatography was developed and validated for efavirenz tablets. The physical chemical characteristics of
Osnir de Sá Viana, Flávia Patrícia Morais Medeiros, Severino Grangeiro-Júnior, Miracy Muniz Albuquerque, Mônica Felts La Roca Soares, José Lamartine Soares-Sobrinho, Lariza Darlene Santos Alves, Larissa Araújo Rolim, Keyla Emanuelle Ramos da Silva, Pedro José Rolim-Neto   +9 more
doaj   +1 more source

Antiretroviral treatment in HIV-1 infected pediatric patients: focus on efavirenz

Pediatric Health, Medicine and Therapeutics, 2014
Beatriz Larru,1 Jessica Eby,2,3 Elizabeth D Lowenthal2,4,51Department of Pediatrics, Division of Infectious Diseases, 2Department of Pediatrics, Division of General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, 3Villanova University,
Larru B, Eby J, Lowenthal ED
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Effect of Efavirenz on Endogenous Progesterone Concentrations and Contraceptive Outcomes among Ugandan HIV Infected Women Coadministering Ethinylestradiol/Levonorgestrel

AIDS Research and Treatment, 2017
This study assessed the effect of efavirenz mid-dose plasma concentrations on mid-luteal endogenous progesterone concentrations and contraceptive outcomes among 49 HIV infected women coadministering ethinylestradiol/levonorgestrel, including 34 HIV ...
Grant Munkwase, Kuteesa R. Bisaso, Othman Kakaire, Sarah Nanzigu   +3 more
doaj   +1 more source

Optimization of solid phase extraction for simultaneous quantification of efavirenz and levonorgestrel in wastewater using HPLC

Frontiers in Environmental Science
This study aims to optimize the SPE parameters for purification and preconcentration of EFV and LVG to enable optimum detection and quantification by LC-20 Prominence High-Performance Liquid Chromatography (HPLC) system.
E. P. Munzhelele, W. B. Ayinde, W. M. Gitari, W. M. Gitari, R. Mudzielwana   +4 more
doaj   +1 more source

Efavirenz Plasma Concentrations and HIV Viral Load in HIV/AIDS-tuberculosis Infection Patients Treated with Rifampicin

Acta Medica Indonesiana, 2016
Aim:to determine the effect of a rifampicin-containing tuberculosis regimen on efavirenz plasma concentrations and viral load in HIV/AIDS-Tuberculosis infection patients who received efavirenz-based antiretroviral therapy.
Nina Mariana, Purwantyastuti Purwantyastuti, Instiaty Instiaty, Adria Rusli   +3 more
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