Results 111 to 120 of about 791,939 (337)

Effect of Total Collimation Width on Relative Electron Density, Effective Atomic Number, and Stopping Power Ratio Acquired by Dual-Layer Dual-Energy Computed Tomography

, 2021
Seongmoon Jung, Bitbyeol Kim, Euntaek Yoon, Jung-In Kim, Jong Min Park, Chang Heon Choi   +5 more
openalex   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Photon molecules in atomic gases trapped near photonic crystal waveguides

, 2015
Realizing systems that support robust, controlled interactions between individual photons is an exciting frontier of nonlinear optics. To this end, one approach that has emerged recently is to leverage atomic interactions to create strong and spatially ...
Caneva, Tommaso, Chang, Darrick E., Douglas, James S.   +2 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Monte Carlo Code for Calculating the Elastic and Inelastic Scattering Cross Section Along with Mean Free Path of Positron Scattering in Kidney, Lung and Thyroid Organs

East European Journal of Physics
This research calculated the total cross sections for positron scattering in kidney, lung, and thyroid tissues along an energy range of 100 eV to 1 MeV.
Hawar M. Dlshad, Jamal M. Rashid
doaj   +1 more source

Improving the Accuracy of the Effective Atomic Number (EAN) and Relative Electron Density (RED) with Stoichiometric Calibration on PCD-CT Images. [PDF]

Sensors (Basel), 2022
Son K, Kim D, Lee S.
europepmc   +1 more source

Parity oscillations of Kondo temperature in a single molecule break junction

, 2012
We study the Kondo temperature ($T_K$) of a single molecule break junction. By employing a numerical renormalization group calculations we have found that $T_K$ depends dramatically upon the position of the molecule in the wire formed between the ...
Resende, B. M. F, Vernek, E.
core   +1 more source

Water equivalence study of metal impregnated PAGAT gel dosimeter in terms of variation of effective atomic number [PDF]

, 2017
P. Sathiyaraj, E. James Jebaseelan Samuel, Murat Kurudirek   +2 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source