Results 41 to 50 of about 14,131,156 (297)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Atomic Energy Commission Reports [PDF]

, 1965
Quarterly progress report on metallurgy research operations at Hanford Atomic Products Operation in Richland ...
Westinghouse Electric Corporation. Atomic Power Division.
core   +3 more sources

Computational Analysis of Gamma-Ray and Fast Neutron Attenuation performance of some Thorium and Uranium Compounds

Brazilian Journal of Radiation Sciences
Evaluation of the radiation shielding effectiveness of some compounds including Fe, Th, Y, Nb, Ta, Ti, and U have been computed for energy absorption and total interaction in the photon energy range from 0.015 to 15 MeV. The effective atomic number (Zeff)
Ahmed Osman
doaj   +1 more source

Identification of Common Minerals Using Stoichiometric Calibration Method for Dual‐Energy CT

Geochemistry, Geophysics, Geosystems, 2021
Medical X‐ray computed tomography (CT) can be used to rapidly and non‐destructively characterize structure and density variations of geological specimens.
Margherita Martini, Pierre Francus, Leonardo Di Schiavi Trotta, Philippe Després   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Dual-layer dual-energy CT for improving differential diagnosis of squamous cell carcinoma from adenocarcinoma at gastroesophageal junction

Frontiers in Oncology, 2022
ObjectiveTo examine the clinical values of dual-energy CT parameters derived from dual-layer spectral detector CT (SDCT) in the differential diagnosis of squamous cell carcinoma (SCC) and adenocarcinoma (AC) of the gastroesophageal junction (GEJ ...
Meihong Wu, Mao Sheng, Ruomei Li, Xinna Zhang, Xingbiao Chen, Yin Liu, Bin Liu, Yongqiang Yu, Xiaohu Li   +8 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Effective atomic number of some rare earth compounds determined by the study of external bremsstrahlung

Journal of Radiation Research and Applied Sciences, 2015
In this paper we report the effective atomic number (Zeff) of some rare earth compounds determined from the measured external bremsstrahlung (EB) intensity due to the incident beta particles emitted by the 90Sr-90Y source. For this purpose the two sample
M.V. Manjunatha, T.K. Umesh
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source