Results 41 to 50 of about 14,777,258 (301)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Computational Analysis of Gamma-Ray and Fast Neutron Attenuation performance of some Thorium and Uranium Compounds

open access: yesBrazilian Journal of Radiation Sciences
Evaluation of the radiation shielding effectiveness of some compounds including Fe, Th, Y, Nb, Ta, Ti, and U have been computed for energy absorption and total interaction in the photon energy range from 0.015 to 15 MeV. The effective atomic number (Zeff)
Ahmed Osman
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

DETERMINATION OF RADIATION SHIELDING PARAMETERS OF COCRFENITIALX ALLOYS BY USING RECENTLY DEVELOPED PHY-X/PSD AND EPIXS SOFTWARES

open access: yesJournal of Amasya University the Institute of Sciences and Technology, 2022
We calculate the radiation shielding parameters of CoCrFeNiTiAlx alloys which consist of mass attenuation coefficient, linear attenuation coefficient, mean free path, half-value layer, total atomic cross section, effective atomic number and effective ...
Nurettin Arpac, Murat Aygun
doaj   +1 more source

Atomic Power Development Associates Report APDA-124 [PDF]

open access: yes, 1960
Report describing the Enrico Fermi Atomic Power Plant, its fast breeder reactor, and heat transport ...
Atomic Power Development Associates
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Identification of Common Minerals Using Stoichiometric Calibration Method for Dual‐Energy CT

open access: yesGeochemistry, Geophysics, Geosystems, 2021
Medical X‐ray computed tomography (CT) can be used to rapidly and non‐destructively characterize structure and density variations of geological specimens.
Margherita Martini   +3 more
doaj   +1 more source

Atomic Power Development Associates Report APDA-108 [PDF]

open access: yes, 1955
Report that generally describes sodium cooled fast reactors, the features and facilities of such a reactor proposed by Atomic Power Development Associates, and then its safety and siting ...
Atomic Power Development Associates
core  

Effective magnetic fields induced by EIT in ultra-cold atomic gases [PDF]

open access: yes, 2005
We study the influence of two resonant laser beams (to be referred to as the control and probe beams) on the centre-of-mass motion of ultra-cold atoms characterized by three energy levels of the Λ-type.
Ohberg, P., Juzeliunas, G., Ruseckas, J.
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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