Results 61 to 70 of about 773,148 (338)

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Dual-layer dual-energy CT for improving differential diagnosis of squamous cell carcinoma from adenocarcinoma at gastroesophageal junction

open access: yesFrontiers in Oncology, 2022
ObjectiveTo examine the clinical values of dual-energy CT parameters derived from dual-layer spectral detector CT (SDCT) in the differential diagnosis of squamous cell carcinoma (SCC) and adenocarcinoma (AC) of the gastroesophageal junction (GEJ ...
Meihong Wu   +8 more
doaj   +1 more source

Effective Quantum Dynamics of Interacting Systems with Inhomogeneous Coupling [PDF]

open access: yes, 2006
We study the quantum dynamics of a single mode/particle interacting inhomogeneously with a large number of particles and introduce an effective approach to find the accessible Hilbert space where the dynamics takes place. Two relevant examples are given:
C. E. López   +5 more
core   +2 more sources

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Optical Flux Lattices for Ultracold Atomic Gases

open access: yes, 2011
We show that simple laser configurations can give rise to "optical flux lattices", in which optically dressed atoms experience a periodic effective magnetic flux with high mean density.
Cooper, N. R.
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Discrepancies in Atomic Data and Suggestions for their Resolutions

open access: yes, 2017
The analysis and modelling of a range of plasmas (for example: astrophysical, laser-produced and fusion), require atomic data for a number of parameters, such as energy levels, radiative rates and electron impact excitation rates, or equivalently the ...
Aggarwal, K. M.
core   +2 more sources

Cavity-Assisted Dynamical Spin-Orbit Coupling in Cold Atoms [PDF]

open access: yes, 2014
We consider ultracold atoms subjected to a cavity-assisted two-photon Raman transition. The Raman coupling gives rise to effective spin-orbit interaction which couples atom's center-of-mass motion to its pseudospin degrees of freedom.
Dong, Lin   +4 more
core   +2 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

PHOTON INTERACTION PARAMETERS OF SOME CHEMICAL TERS OF SOME CHEMICAL COMPOUNDS FOUND IN HARD TISSUE

open access: yesPolytechnic Journal, 2023
Photon interaction parameters of some chemical compounds in hard tissue were investigated in the energy range (1keV-100 GeV) by using the (NistXCom) program. These interaction parameters: mass attenuation coefficients (μρ), effective atomic number (Zeff),
Didar Swara Salih Mrs, Rafet Y Mr.
doaj   +1 more source

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