Results 71 to 80 of about 14,131,156 (297)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Calculated-Experimental Model for Multilayer Shield

open access: yesARO-The Scientific Journal of Koya University, 2016
The effective linear attenuation coefficients and build-up factors for single shield of Al, Fe, Pb, and for multi-layer shield of Al-Pb, Al-Fe, Fe-Pb, Al-Fe-Pb as a function of shield thickness, atomic number, and order of the materials composing the ...
Maan S. Al-Arif, Diyaree O. Kakil
doaj   +1 more source

Atomic Energy Commission Report 149

open access: yes, 1966
From introduction: This is one of a series of three reports on airborne radioactivity surveys in the United States. The reports contain the 185 airborne anomaly maps issued by the U. S.
U.S. Atomic Energy Commission. Grand Junction Office.
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Efficiency of radiation shielding for types automotive glass in the market Iraq: Experimental and theoretical study

open access: yesNext Materials
In this study, the gamma-ray shielding performance of four commercially available automotive windshield glass samples (S1–S4) was investigated through experimental measurements and theoretical calculations.
Mushtaq Abed Al-Jubbori, Mahmood Taha
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Atomic Energy Commission Report NP-283

open access: yes, 1949
The following document is a collection of investigative reports on the victims of the atomic bomb in Japan. Information covers injuries, how the victim was found, if they were protected, where they were when the bomb went off, radiation effects, and ...
Joint Commission for the Investigation of the Effects of the Atomic Bomb in Japan
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Atomic Energy Commission Report AECD-2376

open access: yes, 1947
Technical report summarizing the radioactive properties of two transplutonium elements, atomic number 95 (Americium) and atomic number 96 (Curium)
Seaborg, Glenn T. (Glenn Theodore), 1912-1999
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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