Results 81 to 90 of about 12,005,894 (331)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
ORGAN AND EFFECTIVE DOSE COEFFICIENTS FOR CRANIAL AND CAUDAL IRRADIATION GEOMETRIES: PHOTONS [PDF]
, 2015 K. G. Veinot +2 more
openalex +1 more source
Absorbed radiation dosimetry of the D3-specific PET radioligand [18F]FluorTriopride estimated using rodent and nonhuman primate [PDF]
, 2016 [(18)F]FluorTriopride ([(18)F]FTP) is a dopamine D(3)-receptor preferring radioligand with potential for investigation of neuropsychiatric disorders including Parkinson disease, dystonia and schizophrenia. Here we estimate human radiation dosimetry for [(
Bognar, Christopher +9 more
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
EPPO Bulletin, 2012 Specific scopeThis standard describes the criteria, as well as the experimental procedures, for determining the minimum effective dose of a plant protection product.Specific approval and amendmentFirst approved in 2003–09.Revision mainly to reflect zonal assessment approved in 2012–09.DefinitionFor the purposes of this standard, the ‘minimum effective ...
openaire +1 more source
UJI EFEKTIVITAS EKSTRAK HERBA MENIRAN (Phyllantus niruri L.) SEBAGAI HEPATOPROTEKTOR TERHADAP KADAR BILIRUBIN TOTAL SERUM TIKUS PUTIH (Rattus norvegicus) [PDF]
, 2008 Liver or hepar is one of the very complex and all important organ in metabolism in body. Liver often become target organ because getting mixed up with chemical metabolism which have the character of toxic and also free radical. the free radical and toxic
NAFISAH, AINUN
core