Results 101 to 110 of about 5,339,479 (329)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Estimating virus effective population size and selection without neutral markers

PLoS Pathogens, 2017
By combining high-throughput sequencing (HTS) with experimental evolution, we can observe the within-host dynamics of pathogen variants of biomedical or ecological interest. We studied the evolutionary dynamics of five variants of Potato virus Y (PVY) in
Elsa Rousseau, B. Moury, L. Mailleret, R. Senoussi, A. Palloix, Vincent Simon, Sophie Valière, F. Grognard, F. Fabre   +8 more
semanticscholar   +1 more source

The annual number of breeding adults and the effective population size of syntopic newts (Triturus cristatus, T-marmoratus) [PDF]

, 2001
Pond-breeding amphibians are deme-structured organisms with a population genetic structure particularly susceptible to demographic threats. We estimated the effective number of breeding adults (N-b) and the effective population size (N-e) of the European
Arntzen, W., Burke, T., Hodl, W., Jehle, R., Krupa, A.P.   +4 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

One-step Estimation of Networked Population Size: Respondent-Driven Capture-Recapture with Anonymity [PDF]

, 2017
Population size estimates for hidden and hard-to-reach populations are particularly important when members are known to suffer from disproportion health issues or to pose health risks to the larger ambient population in which they are embedded.
Dombrowski, Kirk, Fellows, Ian, Khan, Bilal, Lee, Hsuan-Wei   +3 more
core   +5 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Population Size in Evolutionary Biology Is More Than the Effective Size

Evolutionary Applications
In population genetics idealized Wright‐Fisher (WF) populations are generally considered equivalent to real populations with regard to the major evolutionary processes that influence genotype and allele frequencies.
Joachim Mergeay
doaj   +1 more source

Genomic diversity characteristics of sheep populations in the Czech Republic, Slovakia, Serbia and Montenegro

Czech Journal of Animal Science
Monitoring the genetic diversity in livestock is a critical component for sustainable management of small and endangered breeds. In this paper we follow up the two most often used metrics of genetic diversity, the average inbreeding coefficients (F) and ...
Gábor Mészáros, Birgit Fürst-Waltl, Johann Sölkner, Hana Vostrá-Vydrová, Jan Calta, Milena Đokić, Božidarka Marković, Dragan Stanojević, Vladan Bogdanovic   +8 more
doaj   +1 more source

Genetic structure as a response to anthropogenic and extreme weather disturbances of a coastal dune dwelling spider, Arctosa sanctaerosae

Ecology and Evolution, 2021
The continued increase in the number of tourists visiting the Northern Gulf Coast (NGC), USA, in the last century, and the resulting sprawl of large cities along the coast, has degraded and fragmented the available habitat of Arctosa sanctaerosae, a wolf
Robert A. Hataway, David H. Reed
doaj   +1 more source

Modelling the hepatitis B vaccination programme in prisons [PDF]

, 2005
A vaccination programme offering hepatitis B (HBV) vaccine at reception into prison has been introduced into selected prisons in England and Wales. Over the coming years it is anticipated this vaccination programme will be extended.
Andrews, Nicholas J., Edmunds, W. John, Gay, N. J., Gilbert, R. L., Gill, O. N., Hope, V. D., Piper, M., Sutton, A. J.   +7 more
core   +2 more sources