Results 101 to 110 of about 3,832,732 (295)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
EVOLUTION OF RELIGIOUS CAPACITY IN THE GENUS HOMO: ORIGINS AND BUILDING BLOCKS
Zygon, 2018 The large, ancient ape population of the Miocene reached across Eurasia and down into Africa. From this genetically diverse group, the chimpanzees, bonobos, gorillas, and humans evolved from populations of successively reduced size.
doaj +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Population structure and variance effective size of red snapper (Lutjanus campechanus) in the northern Gulf of Mexico* [PDF]
, 2006 We assayed allelic variation at 19 nuclear-encoded microsatellites among 1622 Gulf red snapper (Lutjanus campechanus) sampled from the 1995 and 1997 cohorts at each of three offshore localities in the northern Gulf of Mexico (Gulf).
Gold, John R., Saillant, Eric
core
Quantum Criticality in a Bosonic Josephson Junction
, 2012 In this paper we consider a bosonic Josephson junction described by a two-mode Bose-Hubbard model, and we thoroughly analyze a quantum phase transition occurring in the system in the limit of infinite bosonic population.
Buonsante, P. +3 more
core +1 more source
Close-kin methods to estimate census size and effective population size [PDF]
, 2021 Robin S. Waples, Pierre Feutry
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Protein evolution depends on multiple distinct population size parameters
BMC Evolutionary Biology, 2018 That population size affects the fate of new mutations arising in genomes, modulating both how frequently they arise and how efficiently natural selection is able to filter them, is well established.
Alexander Platt +2 more
doaj +1 more source
The largest strongly connected component in Wakeley et al's cyclical pedigree model [PDF]
, 2014 We establish a link between Wakeley et al's (2012) cyclical pedigree model from population genetics and a randomized directed configuration model (DCM) considered by Cooper and Frieze (2004).
Blath, Jochen +2 more
core
Bayesian computation via empirical likelihood
, 2012 Approximate Bayesian computation (ABC) has become an essential tool for the analysis of complex stochastic models when the likelihood function is numerically unavailable.
Beaumont +14 more
core +4 more sources