Results 121 to 130 of about 14,162,835 (267)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

[Effects of climate change on reproductive number of Chagas disease].

open access: yesRevista medica de Chile, 2020
Reproductive number (R0)-maps estimate risk zones of vector-borne diseases and geographical distribution changes under climate change.To map R0 aiming to estimate the epidemiological risk of Chagas disease in Chile, its distribution and possible changes due to the global climate change.We used a relationship between R0 and entomological parameters of ...
Salvador, Ayala   +4 more
openaire   +1 more source

Individual effective reproduction number and generation time.

open access: yes, 2015
Box-plot for the individual for the nosocomial outbreak described in [2] based on the permutations of the duration of illness. It shows the first and third percentiles, the minimum and maximum values, the median, and outliers (red dots).
Elisabeth Fichet-Calvet (218214)   +11 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Mpox outbreak reproduction number estimates

open access: yes
Data as of December 5, 2022CDC is using a model to estimate the effective reproduction number (Rt) for the mpox outbreak in the US. Rt is used to understand the trajectory of an epidemic up to the current time (where we are now).

core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Simulated effective reproduction number (R) and admission prevalence (φ) pairs in replication sample (300 replications).

open access: yes, 2015
Simulated effective reproduction number (R) and admission prevalence (φ) pairs in replication sample (300 replications).
Eleftherios Mylonakis (24103)   +5 more
core   +1 more source

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