Results 121 to 130 of about 7,592,081 (289)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Energy dissipation of moved magnetic vortices
, 2013 A two-dimensional easy-plane ferromagnetic substrate, interacting with a dipolar tip which is magnetised perpendicular with respect to the easy plane is studied numerically by solving the Landau-Lifshitz Gilbert equation.
Magiera, Martin P.
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Evolutionary ApplicationsMany methods are now available to calculate Ne, but their performance varies depending on assumptions. Although simulated data are useful to discover certain types of bias, real empirical data supported by detailed known population histories allow us to ...
Laia Pérez‐Sorribes +3 more
doaj +1 more source
Identification and evaluation of linear damping models in beam vibrations [PDF]
, 1969 Sensitive method, identifying effective damping mechanisms, involves comparing experimentally determined ratio of first to second mode magnification factors related to common point on beam.
Boers, B. L. +2 more
core +1 more source
Long- and short-range correlations in the ab-initio no-core shell model
, 2006 In the framework of the ab-initio no-core shell model (NCSM), we describe the longitudinal-longitudinal distribution function, part of the inclusive (e,e') longitudinal response.
Barrett, Bruce R. +3 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source