Results 91 to 100 of about 397 (188)

Topoisomerase VI is a chirally-selective, preferential DNA decatenase. [PDF]

Elife, 2022
McKie SJ, Desai PR, Seol Y, Allen AM, Maxwell A, Neuman KC.   +5 more
europepmc   +1 more source

A drought stress‐induced MYB transcription factor regulates pavement cell shape in leaves of European aspen (Populus tremula)

New Phytologist, Volume 251, Issue 5, Page 2688-2705, September 2026.
MYB305a promoter expression increases in pavement cells as they grow and acquire their complex shape. Summary Leaf pavement cells of many plant species develop jigsaw puzzle‐like shapes in which neighboring cells interdigitate, providing an ideal model for the study of cell shape regulation.
Sijia Liu, Siamsa M. Doyle, Kathryn M. Robinson, Zahra Rahneshan, Nathaniel R. Street, Stéphanie Robert   +5 more
wiley   +1 more source

The SVP–FRO6 Module Integrates the Control of Leaf Senescence and Flowering in Arabidopsis

Plant, Cell &Environment, Volume 49, Issue 9, Page 7191-7209, September 2026.
ABSTRACT Plants coordinate major developmental transitions by integrating intrinsic genetic programs with environmental signals, where nutrient availability serves as a critical external factor shaping growth and fitness. Iron (Fe), an essential micronutrient for cellular respiration and photosynthesis, is strictly regulated through sophisticated ...
Hyunsu Park, Yeong Seon Yoon, Sanghoon Park, Ukcheol Jeong, Hyeyoung Choi, Hyunwoo Oh, Dovran Shamamedov, Zhonghai Li, Hye Ryun Woo   +8 more
wiley   +1 more source

The Painterly Materiality of Clouds in Antony and Cleopatra and Hamlet

Renaissance Studies, Volume 40, Issue 4, Page 589-608, September 2026.
Abstract This article examines the cloud‐gazing scenes in Antony and Cleopatra and Hamlet through the lens of early modern artistic theory and material practices, particularly the art of limning. Building upon existing philosophical and poetic interpretations of Shakespearean clouds as metaphors for ephemerality and memory, the essay argues that the ...
Anne‐Valérie Dulac
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, Volume 20, Issue 8, Page 1963-1985, August 2026.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, Volume 20, Issue 8, Page 2114-2128, August 2026.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Promising derivatives of rutaecarpine with diverse pharmacological activities. [PDF]

Front Chem, 2023
Li D, Huang Z, Xu X, Li Y.
europepmc   +1 more source

Beyond Binary: Cardiac Patterning as Probabilistic Fate Restriction

BioEssays, Volume 48, Issue 8, August 2026.
Are cardiac progenitors committed to fixed lineages, or do they carry probability distributions over heart regions in the epiblast that resolve during gastrulation? Reanalyzing mouse retrospective clonal data, we find no single lineage tree, instead 361 distinct restriction topologies, consistent with a probabilistic model where epiblast position set ...
Kenzo Ivanovitch
wiley   +1 more source

Constructing national identity in public health crises: a comparative DHA study of China and the United States (2003-2023). [PDF]

Front Public Health
Wu W.
europepmc   +1 more source

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari, Asif Raza, Hannah Johnson, Nuria Martínez‐Sáez, Ignacio Encío, Arun K. Sharma, Carmen Sanmartín, Daniel Plano   +7 more
wiley   +1 more source