Results 81 to 90 of about 394 (185)

ATR Inhibitors in Platinum-Resistant Ovarian Cancer. [PDF]

open access: yesCancers (Basel), 2022
Li S, Wang T, Fei X, Zhang M.
europepmc   +1 more source

Selenium‐Containing 1,4‐Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple‐Negative Breast Cancer Cells

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari   +7 more
wiley   +1 more source

Quantifying Multidimensional Effects in Linear Site Response Using 1D and 2D Simulations of Sedimentary Basins in Wellington, New Zealand

open access: yesEarthquake Spectra, Volume 42, Issue 3, August 2026.
This study quantifies the influence of multidimensional effects on site response in the Wellington region of New Zealand by comparing results from different simulation approaches. Response‐spectral amplification functions from 1D and 2D site response analyses are compared to quantify the magnitude and spatial distribution of multidimensional effects ...
Christopher A. de la Torre   +3 more
wiley   +1 more source

Instrumentos que avaliam a mobilidade de crianças e adolescentes com transtorno do espectro autista: Uma revisão sistemática e mapa de decisão

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 8, Page e118-e132, August 2026.
Objetivos Identificar os instrumentos padronizados usados para avaliar aspectos de mobilidade em crianças e adolescentes com transtorno do espectro autista (TEA), analisar a qualidade de suas propriedades psicométricas e seu nível de evidência, e desenvolver um mapa de decisão clínica para esses instrumentos.
Arthur Felipe Barroso de Lima   +4 more
wiley   +1 more source

The Seismic Expression of Core Complex‐Style Extensional Detachment Faults in Rifted Margins

open access: yesTerra Nova, Volume 38, Issue 4, Page 251-258, August 2026.
ABSTRACT The identification of core complex‐style extensional detachment faults (CCDFs) in rifted margins is crucial for accurately restoring their stratigraphic and thermal histories. Yet recognising CCDFs in seismic reflection images is challenging due to their faint topographic expression; the lack of associated abrupt offset in seismic reflections;
Pauline Chenin   +3 more
wiley   +1 more source

Global Cooling Driving the Increase in Erosion Rates Across the Himalaya Since the Quaternary

open access: yesGeophysical Research Letters, Volume 53, Issue 13, 16 July 2026.
Abstract Late Cenozoic global cooling is well documented, yet its impact on erosion rates in active mountain belts, particularly after the onset of Quaternary glaciation, remain contentious. This ambiguity partially stems from the potential methodological biases in erosion rate quantification, particularly in the Himalaya, where recent studies report ...
Dongxu Cai   +9 more
wiley   +1 more source

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

Black Phosphorus Quantum Dot–Based Hybrid Nanoplatforms: From Surface Reactivity to Multifunctional Integration

open access: yesEngineering Reports, Volume 8, Issue 7, July 2026.
Black phosphorus quantum dot (BPQD) hybrid nanoplatforms integrate tunable optoelectronic properties and surface reactivity for multifunctional applications including dual‐mode biosensing, near‐infrared bioimaging, and self‐powered electronics. Engineering strategies such as covalent passivation and interface design address critical challenges of ...
Faiz Mahmood   +9 more
wiley   +1 more source

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