Results 81 to 90 of about 394 (185)
ATR Inhibitors in Platinum-Resistant Ovarian Cancer. [PDF]
Li S, Wang T, Fei X, Zhang M.
europepmc +1 more source
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Eduardo Angulo‐Elizari +7 more
wiley +1 more source
This study quantifies the influence of multidimensional effects on site response in the Wellington region of New Zealand by comparing results from different simulation approaches. Response‐spectral amplification functions from 1D and 2D site response analyses are compared to quantify the magnitude and spatial distribution of multidimensional effects ...
Christopher A. de la Torre +3 more
wiley +1 more source
Complexes of Emotions in Joseph and Aseneth. [PDF]
Smith T.
europepmc +1 more source
Objetivos Identificar os instrumentos padronizados usados para avaliar aspectos de mobilidade em crianças e adolescentes com transtorno do espectro autista (TEA), analisar a qualidade de suas propriedades psicométricas e seu nível de evidência, e desenvolver um mapa de decisão clínica para esses instrumentos.
Arthur Felipe Barroso de Lima +4 more
wiley +1 more source
Therapeutic Targeting of DNA Replication Stress in Cancer. [PDF]
Gu L, Hickey RJ, Malkas LH.
europepmc +1 more source
The Seismic Expression of Core Complex‐Style Extensional Detachment Faults in Rifted Margins
ABSTRACT The identification of core complex‐style extensional detachment faults (CCDFs) in rifted margins is crucial for accurately restoring their stratigraphic and thermal histories. Yet recognising CCDFs in seismic reflection images is challenging due to their faint topographic expression; the lack of associated abrupt offset in seismic reflections;
Pauline Chenin +3 more
wiley +1 more source
Global Cooling Driving the Increase in Erosion Rates Across the Himalaya Since the Quaternary
Abstract Late Cenozoic global cooling is well documented, yet its impact on erosion rates in active mountain belts, particularly after the onset of Quaternary glaciation, remain contentious. This ambiguity partially stems from the potential methodological biases in erosion rate quantification, particularly in the Himalaya, where recent studies report ...
Dongxu Cai +9 more
wiley +1 more source
DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei +12 more
wiley +1 more source
Black phosphorus quantum dot (BPQD) hybrid nanoplatforms integrate tunable optoelectronic properties and surface reactivity for multifunctional applications including dual‐mode biosensing, near‐infrared bioimaging, and self‐powered electronics. Engineering strategies such as covalent passivation and interface design address critical challenges of ...
Faiz Mahmood +9 more
wiley +1 more source

