Results 61 to 70 of about 397 (188)

From bench to bedside - current clinical and translational challenges in fibula free flap reconstruction. [PDF]

open access: yesFront Med (Lausanne), 2023
Baecher H   +7 more
europepmc   +1 more source

Palaeoglaciations in the Polar and Subpolar Ural Mountains

open access: yesBoreas, EarlyView.
The Ural Mountains form a major physiographic boundary between the East European Plain and West Siberia, both repeatedly glaciated during the Pleistocene by the Barents–Kara ice sheet. Although the present‐day topography reflects significant glacial modification, the extent, chronology and interaction of mountain glaciers with the Barents–Kara ice ...
Bartosz Kurjanski   +6 more
wiley   +1 more source

A simple presentation of the effective topos

open access: yes, 2012
We propose for the Effective Topos an alternative construction: a realisability framework composed of two levels of abstraction. This construction simplifies the proof that the Effective Topos is a topos (equipped with natural numbers), which is the main issue that this paper addresses. In this our work can be compared to Frey's monadic tripos-to-topos
Bernadet, Alexis   +1 more
openaire   +1 more source

New biosensors and transgenic mice for multiplex cGMP imaging

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters   +6 more
wiley   +1 more source

Decellularised Corneal Stromal Lamina With or Without Autologous Adipose‐Derived Adult Stem Cells for Advanced Keratoconus: 1‐Year Results of a Phase I/IIa Clinical Trial

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang   +7 more
wiley   +1 more source

Wee1 kinase differentially regulates maize CDKA2;1a and CDKB1;1

open access: yesThe FEBS Journal, EarlyView.
In eukaryotes, Wee1 kinase inhibits the kinase activity of CDK/Cyc complexes through phosphorylation of a conserved residue in the CDK moiety. Wee1 is also present in plants, but has been scarcely studied. We have studied maize Wee1 regulation of CDKA/CycD2;2a or CDKB/CycD2;2a complexes.
Mingyar N. López‐Hernández   +4 more
wiley   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

open access: yesThe FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras   +3 more
wiley   +1 more source

Politicizing COVID-19 Lingua in Western and Arab Newspapers: A Critical Discourse Analysis. [PDF]

open access: yesInt J Semiot Law, 2023
Elyas T   +7 more
europepmc   +1 more source

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