Results 51 to 60 of about 978,587 (263)

Effector-Triggered Immune Response in Arabidopsis thaliana Is a Quantitative Trait [PDF]

Genetics, 2016
Abstract We identified loci responsible for natural variation in Arabidopsis thaliana (Arabidopsis) responses to a bacterial pathogen virulence factor, HopAM1. HopAM1 is a type III effector protein secreted by the virulent Pseudomonas syringae strain Pto DC3000.
M. Iakovidis, P. J. P. L. Teixeira, M. Exposito-Alonso, M. G. Cowper, T. F. Law, Q. Liu, M. C. Vu, T. M. Dang, J. A. Corwin, D. Weigel, J. L. Dangl, S. R. Grant   +11 more
openaire   +3 more sources

Effector Triggered Immunity: NLR Immune Perception and Downstream Defense Responses [PDF]

The Arabidopsis Book, 2015
Plants have evolved sophisticated surveillance systems to recognize conserved microbial patterns or secreted pathogen effector proteins. Research in Arabidopsis has significantly advanced our understanding of plant immune perception and signaling. Intracellular immune receptors possessing central nucleotide binding and C-terminal leucine rich repeat ...
Yi-Hsuan Chiang, Gitta Coaker
openaire   +1 more source

Effector-triggered defence against apoplastic fungal pathogens [PDF]

, 2014
R gene-mediated host resistance against apoplastic fungal pathogens is not adequately explained by the terms pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) or effector-triggered immunity (ETI).
Mitrousia, G.K., Fitt, B.D.L., Stotz, H.U., Wit, P.J.G.M., de, Fitt, Bruce D.L., Stotz, Henrik, de Wit, Pierre, Mitrousia, Georgia   +7 more
core   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Auto-acetylation on K289 is not essential for HopZ1a-mediated plant defense suppression

Frontiers in Microbiology, 2015
The Pseudomonas syringae type III-secreted effector HopZ1a is a member of the HopZ / YopJ superfamily of effectors that triggers immunity in Arabidopsis.
Jose Sebastian Rufian, Ainhoa eLucía, Alberto P Macho, Begoña eOrozco-Navarrete, Manuel Alberto Arroyo-Mateos, Eduardo Rodriguez Bejarano, Carmen R. Beuzón, Javier eRuiz-Albert   +7 more
doaj   +1 more source

Transcriptomic analysis reveals tomato genes whose expression is induced specifically during effector-triggered immunity and identifies the Epk1 protein kinase which is required for the host response to three bacterial effector proteins [PDF]

, 2014
Plants have two related immune systems to defend themselves against pathogen attack. Initially,pattern-triggered immunity is activated upon recognition of microbe-associated molecular patterns by pattern recognition receptors. Pathogenic bacteria deliver
Dunham, Diane M., Diane M Dunham, Yi Zheng, Zheng, Yi, Pombo, Marina A., Martin, Gregory B., Marina A Pombo, Zhangjun Fei, Gregory B Martin, Noe Fernandez-Pozo, Fernández-Pozo, Noé, Fei, Zhangjun   +11 more
core   +2 more sources

Three LysM effectors of Zymoseptoria tritici collectively disarm chitin‐triggered plant immunity [PDF]

, 2021
Chitin is a major structural component of fungal cell walls and acts as a microbe‐associated molecular pattern (MAMP) that, on recognition by a plant host, triggers the activation of immune responses.
Chen, Hongxin, Bart P. H. J. Thomma, Mesters, J. R., Rudd, Jason, Craig I. MacKenzie, Jeroen R. Mesters, Thomma, Bart, Tian, Hui, Jason J. Rudd, Van den Berg, Grardy, Hui Tian, Tian, H., Van den Berg, G. C. M., MacKenzie, Craig, Grardy C. M. van den Berg, Thomma, B. P. H. J., Mesters, Jeroen, Rudd, J. J., Luis Rodriguez‐Moreno, MacKenzie, C. I., Rodríguez-Moreno, Luis Gabriel, Chen, H., Rodriguez-Moreno, L., Hongxin Chen   +23 more
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Shigella type-III secretion system effectors counteract the induction of host inflammation and cell death

The EMBO Journal
Many enteric bacterial pathogens deliver virulence effectors to counteract host innate immune responses, such as inflammation and cell death, and colonize the intestinal epithelium.
Hiroshi Ashida, Tokuju Okano, Tamako Iida, Poramed Onsoi, Chihiro Sasakawa, Toshihiko Suzuki   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source