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The Effector Function of Allergens [PDF]
Allergens are antigens that generate an IgE response (sensitization) in susceptible individuals. The allergenicity of an allergen can be thought of in terms of its ability to sensitize as well as its ability to cross-link IgE/IgE receptor complexes on mast cells and basophils leading to release of preformed and newly formed mediators (effector activity)
Hazebrouck, Stéphane+2 more
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The rise of necrotrophic effectors [PDF]
This article is a Commentary on Kariyawasam et al. (2022), 233: 409–426 and Richards et al. (2022), 233: 427–442.
Kostya Kanyuka+3 more
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Effector Glycosyltransferases in Legionella [PDF]
Legionella causes severe pneumonia in humans. The pathogen produces an array of effectors, which interfere with host cell functions. Among them are the glucosyltransferases Lgt1, Lgt2 and Lgt3 from L. pneumophila. Lgt1 and Lgt2 are produced predominately in the post-exponential phase of bacterial growth, while synthesis of Lgt3 is induced mainly in the
Belyi, Yury+2 more
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Oxysterols and Their Cellular Effectors [PDF]
Oxysterols are oxidized 27-carbon cholesterol derivatives or by-products of cholesterol biosynthesis, with a spectrum of biologic activities. Several oxysterols have cytotoxic and pro-apoptotic activities, the ability to interfere with the lateral domain organization, and packing of membrane lipids.
Olkkonen, Vesa M.+2 more
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Insights into Phakopsora pachyrhizi Effector–Effector Interactions
The multifaceted role of pathogen-encoded effectors in plant–pathogen interactions is complex and not fully understood. Effectors operate within intricate host environments, interacting with host proteins and other effectors to modulate virulence.
Mingsheng Qi+5 more
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Effector Caspases and Leukemia [PDF]
Caspases, a family of aspartate-specific cysteine proteases, play a major role in apoptosis and a variety of physiological and pathological processes. Fourteen mammalian caspases have been identified and can be divided into two groups: inflammatory caspases and apoptotic caspases.
Ying Lu, Guo-Qiang Chen
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The Complexity of Finding Effectors [PDF]
The NP-hard EFFECTORS problem on directed graphs is motivated by applications in network mining, particularly concerning the analysis of probabilistic information-propagation processes in social networks. In the corresponding model the arcs carry probabilities and there is a probabilistic diffusion process activating nodes by neighboring activated ...
Bulteau, Laurent+4 more
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Effectors and Effector Delivery in Magnaporthe oryzae
Rice blast caused by Magnaporthe oryzae is one of the most destructive fungal diseases of rice and a model for studying fungal-plant interactions. The fungus penetrates plant cells with appressoria and develops the narrow primary invasive hyphae (IH) and, subsequently, the bulbous secondary IH.
Zhang, Shijie, Xu, Jin-Rong
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Strains of Erwinia tracheiphila, causal agent of bacterial wilt of cucurbits, are divided into distinct clades. Et-melo clade strains wilt Cucumis spp. but not Cucurbita spp., thus exhibiting host specificity, whereas Et-C1 clade strains wilt Cucurbita ...
Olakunle I. Olawole+4 more
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Pulmonary aspergillosis is a severe infectious disease caused by some members of the Aspergillus genus, that affects immunocompetent as well as immunocompromised patients.
Maykel Arias+15 more
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