Results 211 to 220 of about 18,981,148 (397)

Libidibia ferreaMature Seeds Promote Antinociceptive Effect by Peripheral and Central Pathway: Possible Involvement of Opioid and Cholinergic Receptors

, 2014
Luis Armando Sawada, Vanessa Sâmia da Conçeição Monteiro, Guilherme Rodrigues Rabelo, Germana Bueno Dias, Maura Da Cunha, José Luíz Martins do Nascimento, Gilmara de Nazareth Tavares Bastos   +6 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Decoding Effector-Specific Parametric Grip-Force Anticipation From fMRI-Data. [PDF]

Hum Brain Mapp
Caccialupi G, Schmidt TT, Blankenburg F.
europepmc   +1 more source

Physical exercise moderates the mediating effect of depression between physical and psychological abuse in childhood and social network addiction in college students [PDF]

Wenjie Jia, Xin Zhang, Yuanyuan Ma, Guoying Yan, Yiyi Chen, Yang Liu   +5 more
openalex   +1 more source

Effect of Caponization on Meat Quality of Greenleg Partridge Cockerels [PDF]

, 2015
Jolanta Calik, Katarzyna Połtowicz, Sylwester Świątkiewicz, J. Krawczyk, Joanna Nowak   +4 more
openalex   +1 more source

The effect of hygrothermal ageing on the delamination of Carbon/epoxy laminates with Core-shell rubber nanoparticle and Micro-fibre thermoplastic veil toughening

, 2023
Sheng Wang, Mehmet Çağatay Akbolat, K.B. Katnam, Zhenmin Zou, Prasad Potluri, Stephan Sprenger, James Taylor   +6 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Negative Frequency-Dependent Selection Promotes Strain Structure in a Plant Pathogen. [PDF]

Ecol Lett
Li S, Laderman E, Märkle H, Yang Y, Bergelson J, Pascual M.   +5 more
europepmc   +1 more source

The Effect of Brewing Time on the Antioxidant Activity of Tea Infusions [PDF]

Anna Winiarska‐Mieczan, Ewa Baranowska‐Wójcik   +1 more
openalex   +1 more source