Results 221 to 230 of about 18,481,212 (402)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

How influenza A virus NS1 impedes transcription of the host cell's messenger RNAs. [PDF]

Npj Viruses
Marc D.
europepmc   +1 more source

Role of PD-1 during effector CD8 T cell differentiation

Proceedings of the National Academy of Sciences of the United States of America, 2018
Eunseon Ahn, K. Araki, M. Hashimoto, Weiyan Li, J. Riley, Jeanne Cheung, A. Sharpe, G. Freeman, B. Irving, R. Ahmed   +9 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Altered dynamics of T cell subsets in peripheral blood impacts disease progression in newly diagnosed multiple myeloma. [PDF]

Biochem Biophys Rep
Vig M, Kumar L, Dubey S, Gupta R.
europepmc   +1 more source

Effect of Packed Height on Liquid Phase H.T.U. for Packed Columns

, 1959
Haruo Hikita, Takeshi Kataoka, Hirohito Kondo   +2 more
openalex   +2 more sources

The effect of training in pitch discrimination. [PDF]

, 1914
Franklin Orion Smith
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Correction: Brucella modulates secretory trafficking via multiple Type IV secretion effector proteins. [PDF]

PLoS Pathog
Myeni S, Child R, Ng TW, Kupko Iii JJ, Wehrly TD, Porcella SF, Knodler LA, Celli J.   +7 more
europepmc   +1 more source

Atomizing Characteristics of Swirl Injection Nozzle : 3rd Report, The Effect of the Physical Properties of Liquid on the Coefficient of Discharge

, 1953
小林 清志
openalex   +2 more sources