Results 91 to 100 of about 2,174,249 (299)

A translocated effector required for bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectors [PDF]

, 2013
Numerous bacterial pathogens secrete multiple effectors to modulate host cellular functions. These effectors may interfere with each other to efficiently control the infection process.
Okujava, Rusudan, Dehio, Christoph, Polus, F, Guye, Patrick, Muriel Vayssier-Taussat, Rusudan Okujava, Florine Polus (580547), Cornelia Halin (574950), Halin, Cornelia, Patrick Guye, Cornelia Halin, Polus, Florine, Christoph Dehio, Okujava, R, Guye, P, Florine Polus, Halin, C, Vayssier-Taussat, M, Vayssier-Taussat, Muriel, Vayssier Taussat, Muriel, Muriel Vayssier-Taussat (247536), Claudia Mistl (580546), Yun-Yueh Lu (182156), Christoph Dehio (200951), Yun-Yueh Lu, Rolink, Antonius G., Antonius G. Rolink (268388), Antonius G Rolink, Lu, Y, Mistl, C, Dehio, C, Lu, Yun-Yueh, Mistl, Claudia, Rolink, AG, Rusudan Okujava (580545), Patrick Guye (200949), Claudia Mistl, Okujava Rusudan, Vayssier-Taussat Muriel, Halin C, Lu YY, Rolink AG, Polus Florine, Guye P, Mistl C, Mistl Claudia, Dehio Christoph, Dehio C, Halin Cornelia, Okujava R, Guye Patrick, Rolink Antonius G., Lu Yun-Yueh, Polus F, Vayssier-Taussat M   +54 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The identification of RABL2 effector proteins.

, 2012
(A) Preferential binding of candidate effector proteins to GTP-RABL2 (active state) over GDP (inactive state) was confirmed by Western blotting of additional affinity column eluates.
Jennifer C. Y. Lo (129648), Mark C. Field (129657), Christopher J. Ormandy (52479), Claire Borg (129652), James C. Whisstock (14021), Christopher C. Goodnow (129666), Anne E. O'Connor (129650), Brett J. Clark (129655), Vicki Adams (129659), Duangporn Jamsai (129649), R. John Aitken (117184), Tomomoto Ishikawa (129660), Belinda Whittle (129664), Moira K. O'Bryan (129667)   +13 more
core   +1 more source

Structures of Phytophthora RXLR effector proteins: a conserved but adaptable fold underpins functional diversity [PDF]

, 2011
Phytopathogens deliver effector proteins inside host plant cells to promote infection. These proteins can also be sensed by the plant immune system, leading to restriction of pathogen growth.
Banfield, Mark J., King, Stuart R. F., Joe Win, Clarke, Thomas A., Thomas A. Clarke, Blumenschein, Tharin M. A., Richard K. Hughes, Kamoun, Sophien, Boutemy, Laurence S., Win, Joe, Laurence S. Boutemy, Sophien Kamoun, Hughes, Richard K., Tharin M.A. Blumenschein, Mark J. Banfield, Stuart R.F. King   +15 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Zinc-finger (ZiF) fold secreted effectors form a functionally diverse family across lineages of the blast fungus Magnaporthe oryzae.

PLoS Pathogens
Filamentous plant pathogens deliver effector proteins into host cells to suppress host defence responses and manipulate metabolic processes to support colonization.
Juan Carlos De la Concepcion, Thorsten Langner, Koki Fujisaki, Xia Yan, Vincent Were, Anson Ho Ching Lam, Indira Saado, Helen J Brabham, Joe Win, Kentaro Yoshida, Nicholas J Talbot, Ryohei Terauchi, Sophien Kamoun, Mark J Banfield   +13 more
doaj   +1 more source

Small-Molecule Inhibitors of the Type III Secretion System

Molecules, 2015
Drug-resistant pathogens have presented increasing challenges to the discovery and development of new antibacterial agents. The type III secretion system (T3SS), existing in bacterial chromosomes or plasmids, is one of the most complicated protein ...
Lingling Gu, Shanshan Zhou, Lanping Zhu, Cuirong Liang, Xin Chen   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Conserved protein folds underpin the diversification of secreted proteins in a fungal pathogen

BMC Microbiology
Background During host colonization, fungal plant pathogens secrete effector-like proteins that alter host cell physiology and target plant-associated microbes.
Thaís C. S. Dal’Sasso, Eva H. Stukenbrock   +1 more
doaj   +1 more source

Toxoplasma Controls Host Cyclin E Expression through the Use of a Novel MYR1-Dependent Effector Protein, HCE1

mBio, 2019
Toxoplasma gondii is an obligate intracellular parasite that establishes a favorable environment in the host cells in which it replicates. We have previously reported that it uses MYR-dependent translocation of dense granule proteins to elicit a key set ...
Michael W. Panas, Adit Naor, Alicja M. Cygan, John C. Boothroyd   +3 more
doaj   +1 more source