Results 51 to 60 of about 2,174,249 (299)

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Salmonella bongori provides insights into the evolution of the Salmonellae [PDF]

, 2011
The genus Salmonella contains two species, S. bongori and S. enterica. Compared to the well-studied S. enterica there is a marked lack of information regarding the genetic makeup and diversity of S. bongori. S.
Parkhill Julian, Fookes, M, Maskell, Duncan, Caterina Mammina, Kingsley Robert A., Fookes, M., Santiviago, CA, Gad Frankel, Georgios S. Vernikos, Gemma C Langridge, Fookes Maria, Vernikos, G.S., Baeumler, AJ, Mammina, C, Nuccio Sean-Paul, Nastasi, A., Seth-Smith, Helena, Contreras Inés, Langridge, GC, Nuccio, SP, Contreras I, Keith S. Robinson, Schroeder GN, Seth Smith H, Frankel Gad, Humphrey Tom, Petty NK, Nicola K Petty, Sanders, M., Kingsley, Robert A, Dougan G, Kingsley, R.A., Helena Seth-Smith, Baumler, Andreas J., Sanders M, Thomson N.R., Nastasi, A, Gemma C. Langridge, Barrow P, Paul Barrow, Nicholas R Thomson, Seth-Smith, H., Blondel, Carlos J., Santiviago, Carlos A, Frankel, G, Vernikos GS, Seth-Smith Helena, Vernikos, Georgios S., Thomas R. Connor, Vernikos Georgios S., Petty, Nicola K., Petty, N.K., Maskell D, Nuccio, S.-P., Kingsley RA, Humphrey, T., Blondel, Carlos J, Connor, Thomas Richard, Humphrey, Tom, Andreas J. Bäumler, Contreras, I., Vernikos, GS, Robinson, KS, Blondel, C.J., Santiviago, Carlos A., Julian Parkhill, Langridge, Gemma C, Parkhill J, Langridge Gemma C., Blondel CJ, Dougan, Gordon, Georgios S Vernikos, Parkhill, Julian, Barrow, P., Langridge, G.C., Gunnar N Schroeder, Connor TR, Thomas R Connor, Nuccio, Sean, Maskell, D, Roberts Mark, Santiviago CA, Roberts M, Robinson, K.S., Robinson Keith S., Thomson, NR, Santiviago, C.A., Contreras, Ines, Frankel G, Roberts, M., Fookes M, Robert A Kingsley, Sean-Paul Nuccio, Sanders Mandy, Bäumler AJ, Nuccio, S-P, Parkhill, J, Mammina Caterina, Mammina, Caterina, Sanders, M, Mark Roberts, Bäumler Andreas J., Schroeder, Gunnar N., Contreras, I, Connor, T.R., Vernikos, Georgios S, Langridge, Gemma C., Connor Thomas R., Nastasi, Antonino, Gunnar N. Schroeder, Bäumler, AJ, Gordon Dougan, Barrow, P, Robinson, Keith S., Nuccio, Sean-Paul, Maskell Duncan, Sanders, Mandy, Humphrey, T, Carlos A Santiviago, Petty Nicola K., Barrow Paul, Thomson, Nicholas R, Thomson, Nicholas R., Blondel Carlos J., Robinson, Keith S, Keith S Robinson, Seth-Smith, H, Maria Fookes, Nuccio SP, Dougan, G., Inés Contreras, Petty, NK, Schroeder, Gunnar N, Tom Humphrey, Connor, Thomas R, Langridge GC, Frankel, G., Blondel, CJ, Robert A. Kingsley, Maskell, D., Parkhill, J., Dougan Gordon, Thomson Nicholas R., Carlos A. Santiviago, Roberts, Mark, Frankel, Gad, Schroeder Gunnar N., Robinson KS, Santiviago Carlos A., Nicola K. Petty, Petty, Nicola K, Thomas Humphrey, Mandy Sanders, Mammina, C., Kingsley, Robert A., Kingsley, RA, Connor, Thomas R., Barrow, Paul, Nastasi Antonino, Schroeder, GN, Schroeder, G.N., Thomson, N.R., Roberts, M, Nastasi A, Duncan Maskell, Humphrey T, Andreas J Bäumler, Nicholas R. Thomson, Bäumler, A.J., Carlos J Blondel, Connor, TR, Fookes, Maria, Dougan, G, Carlos J. Blondel, Bäumler, Andreas J, Antonino Nastasi   +175 more
core   +3 more sources

A fast and accurate computational approach for the distinction of type III and IV secreted effector proteins

四川大学学报. 自然科学版, 2020
Through type Ⅲ, Ⅳ, Ⅵ secretion systems, Gram-negative bacterial effector proteins can be directly injected into host cells, which causes the hosts infected with various diseases.
LIU Feng-Juan, YANG Qing, CHEN Qian, YU Le-Zheng, LI Yi-Zhou   +4 more
doaj  

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

Molecular Systems Biology, 2016
Pathogens deliver complex arsenals of translocated effector proteins to host cells during infection, but the extent to which these proteins are regulated once inside the eukaryotic cell remains poorly defined.
Malene L Urbanus, Andrew T Quaile, Peter J Stogios, Mariya Morar, Chitong Rao, Rosa Di Leo, Elena Evdokimova, Mandy Lam, Christina Oatway, Marianne E Cuff, Jerzy Osipiuk, Karolina Michalska, Boguslaw P Nocek, Mikko Taipale, Alexei Savchenko, Alexander W Ensminger   +15 more
doaj   +1 more source

Allelic Variation and Selection in Effector Genes of Phytophthora infestans (Mont.) de Bary

Pathogens, 2020
Phytophthora infestans is a devastating plant pathogen in several crops such as potato (Solanum tuberosum), tomato (Solanum lycopersicum) and Andean fruits such as tree tomato (Solanum betaceum), lulo (Solanum quitoense), uchuva (Physalis peruviana) and ...
Juan G. Morales, Astrid E. Gaviria, Elizabeth Gilchrist   +2 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Unraveling the Entry Mechanism of Oomycete and Fungal Effector Proteins into host cells [PDF]

, 2015
Oomycetes and fungi facilitate pathogenesis via secretion of effector proteins that have apoplastic and intracellular localizations. These effector proteins have a diverse array of functions that aid in pathogenesis, including modification of defense ...
Lawrence, D., GU, B., Rumore, A. C., Shan, C. B., Tyler, B. M., Capelluto, Daniel G. S., Kale, Shiv D.   +6 more
core  

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source