At the frontier; RXLR effectors crossing the Phytophthora -host interface [PDF]
, 2011 Plants are constantly beset by pathogenic organisms. To successfully infect their hosts, plant pathogens secrete effector proteins, many of which are translocated to the inside of the host cell where they manipulate normal physiological processes and ...
Meijer, H.J.G. +8 more
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The death effector domain protein family [PDF]
Oncogene, 2003 Apoptosis signaling is regulated and executed by specialized proteins that often carry protein/protein interaction domains. One of these domains is the death effector domain (DED) that is predominantly found in components of the death-inducing signaling complex, which forms at the members of the death receptor family following their ligation.
Bryan C, Barnhart +3 more
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Structural Insights into the Effector - Immunity System Tae4/Tai4 from Salmonella typhimurium. [PDF]
PLoS ONE, 2013 Type-6-secretion systems of Gram-negative bacteria are widely distributed needle-like multi-protein complexes that are involved in microbial defense mechanisms.
Juliane Benz +2 more
doaj +1 more source
Riboswitch effectors as protein enzyme cofactors [PDF]
RNA, 2008 The recently identified glmS ribozyme revealed that RNA enzymes, like protein enzymes, are capable of using small molecules as catalytic cofactors to promote chemical reactions. Flavin mononucleotide (FMN), S-adenosyl methionine (SAM), adenosyl cobalamin (AdoCbl), and thiamine pyrophosphate (TPP) are known ligands for RNA riboswitches in the control of
Jesse C, Cochrane, Scott A, Strobel
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The Irish potato famine pathogen Phytophthora infestans translocates the CRN8 kinase into host plant cells [PDF]
, 2012 Phytopathogenic oomycetes, such as Phytophthora infestans, secrete an arsenal of effector proteins that modulate plant innate immunity to enable infection. We describe CRN8, a host-translocated effector of P. infestans that has kinase activity in planta.
Cakir, Cahid +29 more
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Identification and characterisation of a hyper-variable apoplastic effector gene family of the potato cyst nematodes [PDF]
, 2014 Date of Acceptance: 11/08/2014Sedentary endoparasitic nematodes are obligate biotrophs that modify host root tissues, using a suite of effector proteins to create and maintain a feeding site that is their sole source of nutrition. Using assumptions about
Jones, John T. +18 more
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Alternative splicing of a multi-drug transporter from Pseudoperonospora cubensis generates an RXLR effector protein that elicits a rapid cell death. [PDF]
PLoS ONE, 2012 Pseudoperonospora cubensis, an obligate oomycete pathogen, is the causal agent of cucurbit downy mildew, a foliar disease of global economic importance. Similar to other oomycete plant pathogens, Ps.
Elizabeth A Savory +6 more
doaj +1 more source
Mitotic Arrest-Deficient 2 Like 2 (MAD2L2) Interacts with Escherichia coli Effector Protein EspF
Life, 2021 Enteropathogenic (EPEC) and Enterohemorrhagic (EHEC) Escherichia coli are considered emerging zoonotic pathogens of worldwide distribution. The pathogenicity of the bacteria is conferred by multiple virulence determinants, including the locus of ...
Amin Tahoun +9 more
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Prediction of type III secretion signals in genomes of gram-negative bacteria [PDF]
, 2009 Background: Pathogenic bacteria infecting both animals as well as plants use various mechanisms to transport virulence factors across their cell membranes and channel these proteins into the infected host cell.
Löwer, Martin +5 more
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The role of TNRC6 proteins in gene silencing [PDF]
, 2013 Proteins of the GW182 family have recently emerged as key players in miRNAmediated gene silencing. They have been shown to interact with Argonaute proteins, components of the RISC and are assumed to mediate the repression in metazoa. Three paralogues are
Zipprich, Jakob Theophil
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