Results 21 to 30 of about 2,070,236 (251)

The Legionella pneumophila IcmSW complex interacts with multiple Dot/Icm effectors to facilitate type IV translocation.

PLoS Pathogens, 2007
Many gram-negative pathogens use a type IV secretion system (T4SS) to deliver effector proteins into eukaryotic host cells. The fidelity of protein translocation depends on the efficient recognition of effector proteins by the T4SS.
Eric D Cambronne, Craig R Roy
doaj   +1 more source

Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1 [PDF]

, 2010
Fungal and oomycete plant pathogens translocate effector proteins into host cells to establish infection. However, virulence targets and modes of action of their effectors are unknown.
Hein, I., Dixelius, Christina, Hein, I, Hein, Ingo, Bryan, G, Dixelius, C., Kamoun, S., Gilroy, EM, Bos, JIB, Sadanandom, A, Boevink, PC, Gilroy, Eleanor M., Armstrong, MR, Bos, J. I. B., Taylor, RM, Bos, Jorunn I. B., Zhendong, T., Sadanandom, A., Boevink, Petra C., Dixelius, C, Engelhardt, Stefan, Bryan, Glenn, Birch, PRJ, Armstrong, M. R., Engelhardt, S, Hein, Ingo; id_orcid, Harrower, Brian, Kamoun, Sophien, Whisson, Stephen C., Vetukuri, R. R., Birch, Paul R. J.; id_orcid, Bryan, G., Vetukuri, RR, Engelhardt, S., Whisson, S. C., Tian, ZD, Whisson, SC, Boevink, P. C., Bryan, Glenn J., Bos, Jorunn, Gilroy, E. M., Sadanandom, Ari, Birch, Paul R. J., Harrower, B., Harrower, B, Vetukuri, Ramesh R., Birch, P. R. J., Taylor, R. M., Armstrong, Miles R., Taylor, Rosalind M., Zhendong, Tian, Kamoun, S, Tian, Zhendong, Sveriges lantbruksuniversitet., Ramesh, Vetukuri,, Dixelius, Christina,   +55 more
core   +1 more source

Deciphering interplay between Salmonella invasion effectors. [PDF]

, 2008
Bacterial pathogens have evolved a specialized type III secretion system (T3SS) to translocate virulence effector proteins directly into eukaryotic target cells.
Robert J Cain, Koronakis, Vassilis, Cain Robert J., Hayward, RD, Koronakis, V, Hayward, Richard D, Richard D Hayward, Isberg, R.R., Hayward, Richard D., Koronakis, V., Vassilis Koronakis, Cain, Robert J, Cain, RJ, Hayward Richard D., Cain, R.J., Koronakis Vassilis   +15 more
core   +2 more sources

At the frontier; RXLR effectors crossing the Phytophthora -host interface [PDF]

, 2011
Plants are constantly beset by pathogenic organisms. To successfully infect their hosts, plant pathogens secrete effector proteins, many of which are translocated to the inside of the host cell where they manipulate normal physiological processes and ...
Meijer, H.J.G., Francine eGovers, Govers, F., Bouwmeester, K., Klaas eBouwmeester, Harold J. G. Meijer, Francine Govers, Harold. J.G. eMeijer, Klaas Bouwmeester   +8 more
core   +1 more source

bMERB domains are bivalent Rab8 family effectors evolved by gene duplication

eLife, 2016
In their active GTP-bound form, Rab proteins interact with proteins termed effector molecules. In this study, we have thoroughly characterized a Rab effector domain that is present in proteins of the Mical and EHBP families, both known to act in ...
Amrita Rai, Anastasia Oprisko, Jeremy Campos, Yangxue Fu, Timon Friese, Aymelt Itzen, Roger S Goody, Emerich Mihai Gazdag, Matthias P Müller   +8 more
doaj   +1 more source

The tomato Prf complex is a molecular trap for bacterial effectors based on Pto transphosphorylation [PDF]

, 2013
The bacteria Pseudomonas syringae is a pathogen of many crop species and one of the model pathogens for studying plant and bacterial arms race coevolution.
John P Rathjen, Rathjen, John P, Alexi L. Balmuth, Vardis Ntoukakis, Balmuth, Alexi L, Balmuth, Alexi L., Ra M. E. Jones, Tatiana S Mucyn, Gutierrez, Jose R., Jose R. Gutierrez, Mucyn, Tatiana S, Alexi L. Balmuth, Vardis Ntoukakis (223009), Ntoukakis Vardis, Jose R. Gutierrez (278825), Ntoukakis, Vardis, Alexi L. Balmuth (215165), John P. Rathjen (232061), Jose R Gutierrez, Gutierrez, Jose R, Balmuth Alexi L., Vardis Ntoukakis, Jones, Alexandra M., Tatiana S. Mucyn (278824), Jones, Alexandra M. E, Tatiana S. Mucyn¤a, Rathjen John P., Rathjen, John P., Alexi L Balmuth, Jones Alexandra M. E., Mucyn, Tatiana S., John P. Rathjen*¤b, Alexandra M. E. Jones, Gutierrez Jose R., John P. Rathjen, Alexandra M. E. Jones (50010), Tatiana S. Mucyn, Alexandra M E Jones, Mucyn Tatiana S.   +38 more
core   +2 more sources

Structural Insights into the Effector - Immunity System Tae4/Tai4 from Salmonella typhimurium. [PDF]

PLoS ONE, 2013
Type-6-secretion systems of Gram-negative bacteria are widely distributed needle-like multi-protein complexes that are involved in microbial defense mechanisms.
Juliane Benz, Jochen Reinstein, Anton Meinhart   +2 more
doaj   +1 more source

Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells [PDF]

, 1992
Specific antibodies against rap1A and rap1B small GTP-binding proteins were generated by immunization of rabbits with peptides derived from the C-terminus of the processed proteins.
Schwaner, I., Frank, R., Gausepohl, H., Seifert, Roland, Schultz, Günter, Klinz, F. J.   +5 more
core   +1 more source

An RxLR effector from phytophthora infestans prevents re-localisation of two plant NAC transcription factors from the endoplasmic reticulum to the nucleus [PDF]

, 2013
The plant immune system is activated following the perception of exposed, essential and invariant microbial molecules that are recognised as non-self. A major component of plant immunity is the transcriptional induction of genes involved in a wide array ...
McLellan, Hazel, Petra C Boevink, Beynon Jim L., Gomez, Sonia, Beynon, Jim L., Jim L. Beynon (469129), Boevink Petra C., Beynon, Jim, Whisson, Stephen C., Birch, Paul R. J.; id_orcid, Boevink, Petra, Petra C. Boevink (394247), Pritchard Leighton, Armstrong Miles R., Hazel McLellan, Miles R. Armstrong (469126), Gomez Sonia, Pritchard, Leighton, Juan Morales, Jim L Beynon, Hazel McLellan (469125), Armstrong, Miles, Birch, Paul R. J., Sonia Gomez (469127), Birch Paul R. J., Morales, Juan, Leighton Pritchard, Paul R J Birch, Sonia Gomez, Leighton Pritchard (173498), Stephen C Whisson, McLellan Hazel, Armstrong, Miles R., Paul R. J. Birch (132138), Stephen C. Whisson (110493), Boevink, Petra C., Gómez-Galera, Sonia, Miles R Armstrong, Whisson Stephen C., Morales Juan, Whisson, steve, Juan Morales (469128)   +41 more
core   +1 more source

Mitotic Arrest-Deficient 2 Like 2 (MAD2L2) Interacts with Escherichia coli Effector Protein EspF

Life, 2021
Enteropathogenic (EPEC) and Enterohemorrhagic (EHEC) Escherichia coli are considered emerging zoonotic pathogens of worldwide distribution. The pathogenicity of the bacteria is conferred by multiple virulence determinants, including the locus of ...
Amin Tahoun, Hanem El-Sharkawy, Samar M. Moustafa, Lina Jamil M. Abdel-Hafez, Ashraf Albrakati, Manfred Koegl, Juergen Haas, Arvind Mahajan, David L. Gally, Ehab Kotb Elmahallawy   +9 more
doaj   +1 more source