Results 41 to 50 of about 2,174,249 (299)

A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity

Nature Communications, 2018
A growing number of cargo-specific effector proteins are being identified that interact with both dynein and dynactin and form processive dynein-dynactin-effector complexes.
In-Gyun Lee, Mara A. Olenick, Malgorzata Boczkowska, Clara Franzini-Armstrong, Erika L. F. Holzbaur, Roberto Dominguez   +5 more
doaj   +1 more source

Mobile effector proteins on phage genomes [PDF]

Bacteriophage, 2012
Bacteriophage genomes found in a range of bacterial pathogens encode a diverse array of virulence factors ranging from superantigens or pore forming lysins to numerous exotoxins. Recent studies have uncovered an entirely new class of bacterial virulence factors, called effector proteins or effector toxins, which are encoded within phage genomes that ...
Boyd, E. Fidelma, Carpenter, Megan R., Chowdhury, Nityananda   +2 more
openaire   +2 more sources

Repetitive N-WASP–binding elements of the Enterohemorrhagic Escherichia coli Effector EspFU Synergistically Activate Actin Assembly [PDF]

, 2008
Enterohemorrhagic Escherichia coli (EHEC) generate F-actin–rich adhesion pedestals by delivering effector proteins into mammalian cells. These effectors include the translocated receptor Tir, along with EspFU, a protein that associates indirectly with ...
McGhie, E.J., Rosen, M.K., Kenneth G Campellone, Robbins, D., Cheng, HC, Robbins, D, Rosen, MK, Koronakis, V, John M Leong, Siripala, AD, Michael K Rosen, Koronakis, V., McGhie Emma J., Leong, JM, Hayward Richard D., Welch, MD, Campellone Kenneth G., Robbins Douglas, Campellone, K.G., Anosha D Siripala, Cheng, H.-C., Leong, J.M., Leong John M., Hui-Chun Cheng, Emma J McGhie, Cheng Hui-Chun, Hayward, RD, Richard D Hayward, Siripala Anosha D., Welch, M.D., Siripala, A.D., Hayward, Richard D., Douglas Robbins, Vassilis Koronakis, Galán, J.E., Campellone, KG, McGhie, EJ, Matthew D Welch, Rosen Michael K., Koronakis Vassilis, Welch Matthew D., Cheng, Hui-Chun, Robbins, Douglas, Siripala, Anosha D., Koronakis, Vassilis, Campellone, Kenneth Geno, Welch, Matthew D., McGhie, Emma J., Rosen, Michael K., Leong, John M.   +49 more
core   +1 more source

Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells [PDF]

, 1992
Specific antibodies against rap1A and rap1B small GTP-binding proteins were generated by immunization of rabbits with peptides derived from the C-terminus of the processed proteins.
Schwaner, I., Frank, R., Gausepohl, H., Seifert, Roland, Schultz, Günter, Klinz, F. J.   +5 more
core   +1 more source

The Functions of Effector Proteins in Yersinia Virulence [PDF]

Polish Journal of Microbiology, 2016
Abstract Yersinia species are bacterial pathogens that can cause plague and intestinal diseases after invading into human cells through the Three Secretion System (TTSS). The effect of pathogenesis is mediated by Yersinia outer proteins (Yop) and ...
ZHANG, LINGLIN, MEI, MENG, YU, CHAN, SHEN, WENWEN, MA, LIXIN, HE, JIEWANG, YI, LI   +6 more
openaire   +4 more sources

Recognitional Specificity and Evolution in the Tomato–Cladosporium fulvum Pathosystem

Molecular Plant-Microbe Interactions, 2009
The interactions between plants and many biotrophic or hemibiotrophic pathogens are controlled by receptor proteins in the host and effector proteins delivered by the pathogen. Pathogen effectors facilitate pathogen growth through the suppression of host
B. B. H. Wulff, A. Chakrabarti, D. A. Jones   +2 more
doaj   +1 more source

The Pseudomonas syringae effector protein HopZ1a suppresses effector‐triggered immunity [PDF]

New Phytologist, 2010
Featured paper: See Editorial p877
Alberto P, Macho, Carlos M, Guevara, Pablo, Tornero, Javier, Ruiz-Albert, Carmen R, Beuzón   +4 more
openaire   +2 more sources

Predication of the Effector Proteins Secreted by Fusarium sacchari Using Genomic Analysis and Heterogenous Expression

Journal of Fungi, 2022
One of the causative agents of pokkah boeng disease (PBD), which affects sugarcane crops globally, is the fungus Fusarium sacchari. These fungal infections reduce sugar quality and yield, resulting in severe economic losses.
Zhen Huang, Huixue Li, Yuming Zhou, Yixue Bao, Zhenzhen Duan, Caixia Wang, Charles A. Powell, Baoshan Chen, Muqing Zhang, Wei Yao   +9 more
doaj   +1 more source

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain [PDF]

, 2011
Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly understood, NS1 multimerization may autoregulate its actions.
Margaret A Taylor, Richard E. Randall, García-Sastre, A., Hale Benjamin G., Kerry, P.S., Lewis Andrew, Taylor Margaret A., Kerry, Philip S., Andrew Lewis, Kerry Philip S., Hass, C., Benjamin G. Hale, Hale, Benjamin G., Rupert J. Russell, Juan Ayllon, Richard E Randall, Randall Richard E., Hale, B.G., Margaret A. Taylor, Ayllon, Juan, Philip S Kerry, Randall, R.E., Adolfo García-Sastre, Ayllón Barasoain, Juan, Lewis, Andrew, Hass Claudia, Ayllon, J., Rupert J Russell, García Sastre, Adolfo, Taylor, M.A., Lewis, A., García-Sastre Adolfo, Taylor, Margaret A., Hass, Claudia, Ayllon Juan, Russell, R.J., Randall, Richard E., Claudia Hass, Russell, Rupert J., Benjamin G Hale, Russell Rupert J., Philip S. Kerry, Garcia-Sastre, Adolfo, Randall, Richard E.; id_orcid   +43 more
core   +1 more source

Suppression of the MicroRNA Pathway by Bacterial Effector Proteins [PDF]

Science, 2008
Plants and animals sense pathogen-associated molecular patterns (PAMPs) and in turn differentially regulate a subset of microRNAs (miRNAs). However, the extent to which the miRNA pathway contributes to innate immunity remains unknown.
Navarro, L., Jay, F., Nomura, K., He, Sy, Voinnet, O.   +4 more
openaire   +3 more sources