Results 51 to 60 of about 406,957 (282)

Genomic and transcriptomic analyses of Phytophthora cinnamomi reveal complex genome architecture, expansion of pathogenicity factors, and host-dependent gene expression profiles

Frontiers in Microbiology
Phytophthora cinnamomi is a hemibiotrophic oomycete causing Phytophthora root rot in over 5,000 plant species, threatening natural ecosystems, forestry, and agriculture. Genomic studies of P.
Aidan C. Shands, Guangyuan Xu, Rodger J. Belisle, Shirin Seifbarghi, Natasha Jackson, Aureliano Bombarely, Liliana M. Cano, Patricia M. Manosalva   +7 more
doaj   +1 more source

A transcriptional regulatory mechanism finely tunes the firing of type VI secretion system in response to bacterial enemies [PDF]

, 2017
The ability to detect and measure danger from an environmental signal is paramount for bacteria to respond accordingly, deploying strategies that halt or counteract potential cellular injury and maximize survival chances. Type VI secretion systems (T6SSs)
Feldman, Mario F, Lazzaro, Martina, Vescovi, Eleonora Garcia   +2 more
core   +2 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Direct evidence of host-mediated glycosylation of NleA and its dependence on interaction with the COPII complex

Gut Microbes
Non-LEE-encoded Effector A (NleA) is a type III secreted effector protein of enterohaemorrhagic and enteropathogenic Escherichia coli as well as the related mouse pathogen Citrobacter rodentium.
Lindsay Burns, François Le Mauff, Samantha Gruenheid   +2 more
doaj   +1 more source

The Effector Repertoire of the Hop Downy Mildew Pathogen Pseudoperonospora humuli

Frontiers in Genetics, 2020
Pseudoperonospora humuli is an obligate biotrophic oomycete that causes downy mildew (DM), one of the most destructive diseases of cultivated hop that can lead to 100% crop loss in susceptible cultivars. We used the published genome of P.
Savithri Purayannur, Liliana M. Cano, Liliana M. Cano, Megan J. Bowman, Megan J. Bowman, Kevin L. Childs, David H. Gent, Lina M. Quesada-Ocampo   +7 more
doaj   +1 more source

Basal rot of narcissus : understanding pathogenicity in fusarium oxysporum f. sp. narcissi [PDF]

, 2019
Fusarium oxysporum is a globally distributed soilborne fungal pathogen causing root rots, bulb rots, crown rots and vascular wilts on a range of horticultural plants. Pathogenic F.
Armitage, Andrew D., Clarkson, John P., Handy, Claire, Harrison, Richard J., Hulin, Michelle T., Jackson, Alison C., Taylor, Andrew   +6 more
core   +2 more sources

GEF-effector interactions [PDF]

Cellular Logistics, 2014
Members of the Arf family of small GTP-binding proteins, or GTPases, are activated by guanine nucleotide exchange factors (GEFs) that catalyze GDP release from their substrate Arf, allowing GTP to bind. In the secretory pathway, Arf1 is first activated by GBF1 at the cis-Golgi, then by BIG1 and BIG2 at the trans-Golgi and trans-Golgi network (TGN ...
openaire   +2 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Comparative Analysis of Host-Associated Variation in Phytophthora cactorum

Frontiers in Microbiology, 2021
Phytophthora cactorum is often described as a generalist pathogen, with isolates causing disease in a range of plant species. It is the causative agent of two diseases in the cultivated strawberry, crown rot (CR; causing whole plant collapse) and leather
Charlotte F. Nellist, Charlotte F. Nellist, Andrew D. Armitage, Andrew D. Armitage, Helen J. Bates, Helen J. Bates, Maria K. Sobczyk, Maria K. Sobczyk, Matteo Luberti, Laura A. Lewis, Laura A. Lewis, Richard J. Harrison, Richard J. Harrison   +12 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source