Results 161 to 170 of about 11,135 (204)

Modulating efferocytosis in the intestinal epithelial cells during colorectal cancer. [PDF]

Front Oncol
Boeckaerts L, Aaes TL, Scheirlinckx E, Choi SM, Incik Y, Gonçalves A, Hochepied T, Vereecke L, Ravichandran KS.   +8 more
europepmc   +1 more source

Exclusion of Notch from the contact site during efferocytosis restricts anticancer immunity. [PDF]

Nat Immunol
Li Z, Xu B, Sharma P, Guy C, Boada-Romero E, Verbist K, Guo A, Mari L, Poudel S, Yang M, Green DR.   +10 more
europepmc   +1 more source

Targeting GPR34 in damage-associated macrophages enhances anti-tumor immunity and the efficacy of Surufatinib in pancreatic cancer. [PDF]

Signal Transduct Target Ther
Guo X, Liu Y, Li T, An X, Song Y, Xu P, Huang J, Zou Y, Xu B, Xie Y, Li Z, Meng C, Zhao T, Wang X, Wang H, Gao C, Zhou X, Yu J, Gao S, Hao J.   +19 more
europepmc   +1 more source

Phosphatidylserine-Dependent Clearance of Damaged Red Blood Cells by Liver Sinusoidal Endothelial Cells in Alcohol-Related Liver Disease. [PDF]

Biology (Basel)
Li S, Zheng C, Zha X, Mueller J, Dropmann A, Hammad S, Dooley S, Mueller S.   +7 more
europepmc   +1 more source

Death as rebirth: how efferocytosis drives tissue repair and disease treatment. [PDF]

Front Immunol
Duan X, Han S, Bian Y, Yuan Y, Shen J, Dai Y, Mi J, Wang Z.   +7 more
europepmc   +1 more source

Phytochemical Monomers Derived from Traditional Chinese Medicine May Prevent and Treat Atherosclerosis by Modulating the Macrophage Mitochondrial-Lysosomal Senescence Axis. [PDF]

Int J Gen Med
Zhao H, Ren W, Jiang H, Zhou R, Deng Y, Huang H, Wang P.   +6 more
europepmc   +1 more source

Efferocytosis and Respiratory Disease

International Journal of Molecular Sciences, 2023
Cells are the smallest units that make up living organisms, which constantly undergo the processes of proliferation, differentiation, senescence and death. Dead cells need to be removed in time to maintain the homeostasis of the organism and keep it healthy. This process is called efferocytosis.
Guoqiang Wang, Xu Zuo, Fang Wang
exaly   +3 more sources

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Macrophage efferocytosis in atherosclerosis

Scandinavian Journal of Immunology, 2023
AbstractThis paper presents the role of macrophage efferocytosis, the process of elimination of apoptotic bodies—elements formed during vascular atherosclerosis. The mechanisms of macrophage efferocytosis are presented, introducing the specific signals of this process, that is, ‘find me’, ‘eat me’ and ‘don't eat me’.
Wiesław Deptuła, Beata Tokarz-Deptuła, Anhelli Syrenicz   +2 more
exaly   +3 more sources

The Role of Efferocytosis in Atherosclerosis [PDF]

Circulation, 2017
The necrotic core has long been a hallmark of the vulnerable atherosclerotic plaque. Although apoptotic cells are cleared quickly in almost all other tissue beds, their removal appears to be significantly impaired in the diseased blood vessel. Emerging evidence indicates that this phenomenon is caused by a defect in efferocytosis, the process by which ...
Nicholas Leeper, Irving Weissman, Yoko Kojima   +2 more
exaly   +3 more sources

What’s the deal with efferocytosis and asthma?

Trends in Immunology, 2021
Mucosal sites, such as the lung, serve as crucial, yet vulnerable barriers to environmental insults such as pathogens, allergens, and toxins. Often, these exposures induce massive infiltration and death of short-lived immune cells in the lung, and efficient clearance of these cells is important for preventing hyperinflammation and resolving ...
Donald Cook, Jennifer Martinez
exaly   +3 more sources